Haernoglobin types in Norwegian horses

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Equine marker genes. Polymorphism for transferrin alleles, Tf^F1 and Tf^F2, in Thoroughbreds

McGuire

Weitkamp

1980

“…Using starch gel electrophoresis these authors observed three phenotypes which seemed to be controlled by a pair of codominant, autosomal alleles, which they designated uA and uB. Other authors reporting on the horse albumins have confirmed this genetic theory (Braend, 1964;Braend and Efremov, 1965;Gahne, 1966;Osterhoff, 1967;Bengtsson et al, 1968). In addition to the nomenclature established by Stormont and Suzuki (1963), designating the fast migrating albumin zone A and the slow one B, another nomenclature was introduced by Braend and Efremov (1965).…”

Section: Introductionmentioning

confidence: 95%

A third allele in the horse albumin system

Sandberg

1972

Starch gel electrophoresis according to Gahne (1966) reveals three new phenotypes designated FI, I and IS in horse serum albumin. Family material comprising 97 sire families with a total number of 2742 foals and their dams and population material comprising 2867 adult horses representative of the Swedish Trotter breed were examined. The results were consistent with a genetic theory of three codominant, autosomal alleles F, I and S controlling the six albumin phenotypes observed. The gene frequencies were estimated to be 0.489, 0.049 and 0.462, respectively, for the F, I and S genes in the Swedish Trotter breed. The risk of making false exclusions in paternity controls in the albumin system, if the I allele is not considered, is discussed.

“…In starch gel electrophoresis the pattern of each variant consists of a strong anodal zone and a weaker cathodal zone. Two atypical variants, Tf C and Tf E, were also described (Braend, 1964) differing from the typical pattern by I I3 the presence of two zones of about equal intensity. Tf C is slightly faster and Tf E slightly slower than Tf D.…”

Section: Introductionmentioning

confidence: 98%

Partial characterization of horse transferrin heterogeneity with respect to the atypical type, Tf C

Stratil¹,

Glasnák²

1981

words: h o rse , trans f e r r i n , heterogeneity , pol y m o rp h is m SummaryIn starch gel electrophoresis of horse sera each transferrin variant is formed by a strong anodal band and a weaker cathodal band. An 'atypical' variant, Tf C, has two zones of about equal intensity. Family data show that Tf C is genetically controlled by an allele Tf C at the Tf locus. Frequencies of transferrin alleles in various horse breeds are also presented.After isolation and fractionation of individual transferrin variants (Tf 0, Tf D, Tf C) on DEAE-Sephadex, additional weak bands were detected. The two main zones of each variant were isolated in a pure state and treated with neutaminidase. In all three variants studied the electrophoretic mobility of the slower band (2a) was decreased in two steps, and the faster band (4b) in four steps. The mobilities of bands derived from the fast zone (4b) were slower than mobilities of corresponding bands derived from the slow zone (2a). These results suggest the presence of two sialic acid residues in the slow zone, and of four residues in the fast zone. Residual heterogeneity was independent of sialic acid.