Haemovigilance procedure in transfusion medicine

Faber, Jean‐Claude

doi:10.1038/sj.thj.6200427

Cited by 17 publications

(13 citation statements)

References 6 publications

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“…Hence, national haemovigilance systems linked to an international network are becoming indispensable elements of blood product safety and quality. Combined with the development and implementation of sensitive and affordable detection and inactivation approaches, these measures can make blood transfusion a safer form of therapy even in places where the risks to date have to be considered significant [5,6,144,145].…”

Section: Resultsmentioning

confidence: 99%

“…In order to maintain the integrity, purity and adequacy of the blood supply new donor screening assays, donor deferral and pathogen inactivation of blood components need to be balanced against the undue loss of potential donors because of overly stringent exclusion criteria. These efforts would ideally be supported by national and international haemovigilance networks that help identify emerging new TTI threats; by facilitating quality assurance, quality control and the ability to monitor all steps in the transfusion chain ( Figure 1) [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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Transfusion-transmitted infections

et al. 2007

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Although the risk of transfusion-transmitted infections today is lower than ever, the supply of safe blood products remains subject to contamination with known and yet to be identified human pathogens. Only continuous improvement and implementation of donor selection, sensitive screening tests and effective inactivation procedures can ensure the elimination, or at least reduction, of the risk of acquiring transfusion transmitted infections. In addition, ongoing education and up-to-date information regarding infectious agents that are potentially transmitted via blood components is necessary to promote the reporting of adverse events, an important component of transfusion transmitted disease surveillance. Thus, the collaboration of all parties involved in transfusion medicine, including national haemovigilance systems, is crucial for protecting a secure blood product supply from known and emerging blood-borne pathogens.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Transfusion-transmitted infections

et al. 2007

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“…The most predominant bacteria isolated are usually commensals of the skin or gastrointestinal tract flora and the majority of isolates were Gram-positive aerobic pathogens (nearly 75%) [12].…”

Section: Introductionmentioning

confidence: 99%

Bacterial Contamination of Stored Blood Ready for Transfusion at a Referral Hospital in Ethiopia

Dagnew¹

2014

J Clinic Res Bioeth

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Background: After the discovery of Human Immuno -deficiency virus, screening of blood donors practically reduced viral pathogens. However, transfusion associated bacterial sepsis, which causes high mortality and morbidity remain an important public health concern, has been received very little attention in the African set up including Ethiopia.Objective: The aim of this study was to determine the prevalence of bacterial contamination of blood and their antibiotic susceptibility pattern at Debre Markos referal hospital, North West Ethiopia. Methods:A facility based cross-sectional study was conducted using randomly sampled 120 whole blood units. The blood samples were obtained from screened, stored whole blood. All laboratory activities were carried out as Clinical and Laboratory Standards Institute (CLSI) protocol. Data were entered and analyzed using SPSS version 16 software. P<0.005 is statistically significant.

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“…One of the main purposes of developing a hemovigilance program is to improve reporting of transfusion related adverse events and subsequent data-driven improvement in BT practices [1].It was first introduced in France in 1993 where it was mandatory while first voluntary reporting system was introduced in United Kingdom in 1996. Since then the developed countries have taken a lead in the hemovigilance programme [2], however Asian countries like India are still lacking a well established system for hemovigilance. A hemovigilance program of India was launched in December 2012 with an initial road map for 5 years.…”

Section: Introductionmentioning

confidence: 99%

Active Hemovigilance Significantly Improves Reporting of Acute Non-infectious Adverse Reactions to Blood Transfusion

Agnihotri

2015

Indian J Hematol Blood Transfus

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One of the key purposes of a hemovigilance program is to improve reporting of transfusion related adverse events and subsequent data-driven improvement in blood transfusion (BT) practices. We conducted a study over 3 years to assess the impact of healthcare worker training and an active feedback programme on reporting of adverse reactions to BTs. All hospitalized patients who required a BT were included in the study. Healthcare workers involved in BT to patients were sensitized and trained in adverse reaction reporting by conducting training sessions and meetings. All the transfused patients were 'actively' monitored for any acute adverse reaction by using a uniquely coded blood issue form. A total of 18,914 blood components transfused to 5785 different patients resulted in 61 adverse reaction episodes. This incidence of 0.32 % in our study was found to be significantly higher (p \ 0.005) than that reported from the same region in the past. Red blood cell units were the most frequently transfused component and thus most commonly involved in an adverse reaction (42.6 %), however apheresis platelets had the highest chance of reaction per unit transfused (0.66 %). There was no mortality associated with the BT during the study period. An active surveillance program significantly improves reporting and management of adverse reactions to BTs.

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Haemovigilance procedure in transfusion medicine

Cited by 17 publications

References 6 publications

Transfusion-transmitted infections

Transfusion-transmitted infections

Bacterial Contamination of Stored Blood Ready for Transfusion at a Referral Hospital in Ethiopia

Active Hemovigilance Significantly Improves Reporting of Acute Non-infectious Adverse Reactions to Blood Transfusion

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