Haemostasis part 2: medications that affect haemostasis

McCormick, Neal J; Moore, Ursula; Meechan, J G; Arshaghi, Ali

doi:10.12968/denu.2014.41.5.395

Cited by 12 publications

(7 citation statements)

References 5 publications

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“…Also for oral hematomas the most frequent causes seem to be teeth extractions [29] and dental implants insertion [3,[30][31][32][33] , where the perforation of the lingual cortex and the resulting hematoma may necessitate tracheotomy in severe cases. Post-extraction bleeding is a frequently observed complication [34] and can generally be justified by the exhaustion of the effect of the vasoconstrictor contained in the local anesthetic [10] . In lower molars this complication occurs in 0.6% of cases, while for those in the upper arch in 0.4% [35] .…”

Section: Resultsmentioning

confidence: 99%

Vascular-nerve complications following oral surgery: hematoma and neuroma: A literature review

Guerrieri¹,

Oliveira²,

Arosio³

et al. 2021

Int. J. Appl. Dent. Sci.

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Introduction: Oral traumas and surgery frequently lead to injuries such as neuromas and hematomas. Materials and Methods: PubMed was searched up using the keywords: "oral traumatic neuroma", "neuroma dental implant" and "oral hematoma". Works about oral surgery were considered. Results: In some of the studies included in this review, traumatic neuroma was found following dental extraction; others following chin augmentation and sagittal osteotomy of the mandible. Implant surgery also appears to be linked to the development of traumatic neuromas. Bilateral bifid mandibular canal is a rare anatomic variation which, if present, can lead to the neuroma following surgery of the lower third molar and the placement of dental implants. The vast majority of cases of hematoma are consequent to oral surgery (rarely have spontaneous hematomas have been described in patients taking antiplatelets or anticoagulants). Conclusion:The literature shows a concrete risk of hematoma and traumatic neuroma following oral or maxillofacial surgery. Particular attention should be paid to patients with coagulation abnormalities.

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Section: Resultsmentioning

confidence: 99%

Vascular-nerve complications following oral surgery: hematoma and neuroma: A literature review

Guerrieri¹,

Oliveira²,

Arosio³

et al. 2021

Int. J. Appl. Dent. Sci.

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“…Conventionally, patients get discharged with instructions to remove the pressure pack by themselves after about an hour. Instances of PEB following pressure pack removal are frequent complications, causing patients to return to the clinic [23]. This can be avoided if the pressure pack can be removed and hemostasis can be ensured before the patient's discharge from the clinic.…”

Section: Discussionmentioning

confidence: 99%

The Optimal Hemostasis Duration After Tooth Extraction: A Randomized Controlled Trial

Yerragudi¹,

Chawla²,

Kalidoss³

et al. 2023

Cureus

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BackgroundThere is a lack of evidence-based practice regarding the duration of pressure pack placement following tooth extraction. This study aimed to compare the incidence of post-extraction bleeding following 60 minutes versus 10 minutes of pressure pack placement. MethodologyA randomized controlled trial was conducted at a tertiary care hospital and included patients requiring intraalveolar tooth extractions. Patients were randomly allocated into the experimental group or control group by a permuted block randomization method. A blinded observer noted the incidence of post-extraction bleeding. Categorical variables were summarized as frequency and percentage. The chi-square test was used for intergroup statistical analysis. P-values <0.05 were considered statistically significant. ResultsThere were 528 participants, 264 of whom were allocated to each group. The incidence of post-extraction bleeding was 8% and 6.8% in the experimental and control groups, respectively. On bivariate analysis, there was no statistically significant difference between the two groups (p = 0.618; relative risk with 95% confidence interval = 1.0). ConclusionsIn the majority of cases, hemostasis was achieved in 10 minutes. Therefore, removing the pressure pack after 10 minutes may be advised to ensure hemostasis and, ultimately, save chairside time.

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“…Tooth extraction is the most frequently performed oral surgical procedure 1 . The main complications after tooth extraction include swelling, pain, infection and bleeding 2 . Of these, bleeding requires urgent management and, at times, additional treatment, such as re‐haemostasis or hospitalisation 3…”

Section: Introductionmentioning

confidence: 99%

“…1 The main complications after tooth extraction include swelling, pain, infection and bleeding. 2 Of these, bleeding requires urgent management and, at times, additional treatment, such as rehaemostasis or hospitalisation. 3 There has been much discussion regarding the causes of postextraction bleeding.…”

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confidence: 99%

Analysis of post‐extraction bleeding in patients taking antithrombotic therapy using data from the longevity improvement and fair evidence study

et al. 2023

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BackgroundSeveral studies have investigated post‐extraction bleeding in patients on antithrombotic therapy, but most included a small sample size.ObjectiveThis study aimed to analyse post‐extraction bleeding in patients on antithrombotic therapy using data from a large database.Materials and MethodsClaims data of National Health Insurance and Late‐Stage Elderly Healthcare System enrollees who underwent tooth extraction between October 2014 and March 2019 (n = 107 767) in a large multiregional cohort study (Longevity Improvement and Fair Evidence study) were included. Antithrombotic therapy was determined based on the drug codes used at the time of tooth extraction (classified into six groups: no antithrombotic, single antiplatelet, dual antiplatelet, Direct Oral Anticoagulant, warfarin and combined antiplatelet and anticoagulant therapies). The outcome was defined as the presence of “post‐extraction bleeding” as a receipt disease name in the same month as tooth extraction. To examine the association between antithrombotic therapy and post‐extraction bleeding in detail, multiple logistic regression analysis was performed with post‐extraction bleeding as the objective variable; each antithrombotic therapy as the explanatory variable; and age, sex and comorbidities as adjustment variables.ResultsAntithrombotic therapy was administered in 14 343 patients (13.3%), and post‐extraction bleeding was observed in 419 patients (0.4%). The rate of post‐extraction bleeding was significantly lower in the no antithrombotic therapy and single antiplatelet groups than that in the other groups (odds ratio: 2.00–9.02).ConclusionThe frequency of post‐extraction bleeding is high in patients on anticoagulation or dual antithrombotic therapy. Therefore, careful preparation before extraction is necessary in these patients.

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Haemostasis part 2: medications that affect haemostasis

Cited by 12 publications

References 5 publications

Vascular-nerve complications following oral surgery: hematoma and neuroma: A literature review

Vascular-nerve complications following oral surgery: hematoma and neuroma: A literature review

The Optimal Hemostasis Duration After Tooth Extraction: A Randomized Controlled Trial

Analysis of post‐extraction bleeding in patients taking antithrombotic therapy using data from the longevity improvement and fair evidence study

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