Haemostasis in Thyroid Surgery: Collagen-Fibrinogen-Thrombin Patch versus Cellulose Gauze—Our Experience

Tartaglia, Nicola; Lascia, Alessandra Di; Lizzi, Vincenzo; Cianci, Pasquale; Fersini, Alberto; Ambrosi, Antonio; Neri, Vincenzo

doi:10.1155/2016/3058754

Cited by 16 publications

(13 citation statements)

References 16 publications

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“…The topical haemostatic agent collagen fibrinogen and thrombin patch (CFTP) had previously been used in thyroid surgery and has shown efficacy in controlling oozing bleeding as well as in reducing the drainage volume [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Measuring neck circumference to predict and detect haemorrhage following thyroid surgery. A case series and literature review

Ezzy

Elshafei

Sharaan

2021

Journal of Surgical Case Reports

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Post-thyroidectomy bleeding is a fortunately rare but potentially life-threatening complication that may increase postoperative morbidity and hospital stay. In this case series, we demonstrate the relation between the measurement of neck circumference and haemorrhage following thyroid surgery and the value of this measurement in predicting post-thyroidectomy haemorrhage. Currently, there is no simple and reliable method available for the early detection of post-thyroidectomy bleeding. Continuous pressure measurement could be a potential tool for the early detection of haemorrhage but is invasive, and more data are required to recommend threshold values for revision surgery. Early recognition and prompt surgical intervention are key to the management of cervical haematoma. Measurement of the neck circumference is a valuable adjunct tool in the early recognition of post-thyroidectomy bleeding. In this case series, we concluded that a 4-cm increase in neck circumference may trigger the clinical decision for cervical exploration.

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Section: Discussionmentioning

confidence: 99%

Measuring neck circumference to predict and detect haemorrhage following thyroid surgery. A case series and literature review

Ezzy

Elshafei

Sharaan

2021

Journal of Surgical Case Reports

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“…This study was in line with our study concerning drain output and HB decrease. In 2016, the results of a study by Tartaglia et al on patients undergoing thyroid surgery indicated that the use of collagen-fibrinogen-thrombin patch reduced the amount of postoperative drainage, as well as bleeding-related complications (30). The Payani et al study used topical fibrinogen on the precordium in open cardiac surgery.…”

Section: Discussionmentioning

confidence: 99%

Is Intra-Articular Administration of Fibrinogen Effective in Postoperative Total Knee Arthroplasty Blood Loss? A Randomized Clinical Trial

et al. 2020

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Objectives: The purpose of this study was to evaluate the effect of intra-articular injection of fibrinogen on postoperative bleeding following total knee arthroplasty. Methods: A double-blind randomized clinical trial was conducted on 40 patients aged 40 - 70 years under spinal anesthesia candidate for total knee arthroplasty in Golestan hospital, Ahwaz, Iran, in 2017-2018. Patients were divided into fibrinogen intra-articular injection (n = 20) and control (n = 20) groups. The amounts of blood loss and blood transfusion requirement were recorded. Hemoglobin (Hb), hematocrit (HCT), international normalized ratio (INR), platelet (PLT), prothrombin time (PT), and partial thromboplastin time (PTT) were recorded before and after the surgery. Results: There was no significant difference in the average amount of intraoperative blood loss between the groups (P > 0.05). The average amount of blood loss 24 hours after the surgery was significantly lower in the fibrinogen group than in the control group (fibrinogen group 350.61 ± 120.32 cc; control group 540.00 ± 170.21 cc; P = 0.0002). There were significant differences in transfusion between the groups (fibrinogen group 250 ± 20 cc; control group 350 ± 50 cc; P < 0.0001). There was a significant difference between the two groups in 24 h postoperative Hb and HCT (P < 0.001). Conclusions: Intra-articular fibrinogen administration may reduce acute bleeding and can be used as an effective intervention to prevent further bleeding and the need for transfusion in patients undergoing total knee arthroplasty.

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“…Tartaglia et al 17 focused on comparing the efficacy of collagen patch coated with human fibrinogen and human thrombin (CFTP) and oxidized regenerated cellulose gauze versus traditional hemostatic procedures in thyroid surgery. In this study, 226 patients were included.…”

Section: Discussionmentioning

confidence: 99%

Effect of fibrin vs cellulose based haemostatic agents with traditional haemostatic procedures in thyroid surgery

Karanikolić¹,

Miodagl²,

Djordjevic³

et al. 2017

Pak J Med Sci

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Objective:To compare the efficacy of fibrin-based hemostat and cellulose-based hemostat with traditional procedures in patients undergoing thyroid surgery.Methods:Between January 2012 and December 2016, 255 patients were scheduled to undergo total thyroidectomy at Surgical Clinic Nis. The patients were randomized to: Group-I use of classic surgical procedures to achieve hemostasis, Group-II use Surgicel and Group-III use BeriplasResults:A statistically significant reduction of surgical time was found for Group-I compared with Group-II and III (p≤0.01 for both groups). Statistically significant reduction of intraoperative blood loss was found for Group-I compared with Group-II from 102.3mL vs. 86.1mL (p≤0.01) as well as compared to Group-III (mean 77.4mL, p≤0.01). Removal of the wound drain occurred sooner in the Group-II and III compared with Group-I (mean 37.1h vs. 40.1h, p≤0.05; mean 31.2h vs. 40.1h, p≤0.01). There were no significant differences in terms of postoperative morbidity among the groups.Conclusions:Fibrin based haemostat seems to be an effective hemostatic agent for patients undergoing thyroid surgery. We suggest that, where appropriate, this fibrin-based haemostat should be used as a first line hemostatic agent in thyroidectomy in combination with conventional surgical means of hemostasis.

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Haemostasis in Thyroid Surgery: Collagen-Fibrinogen-Thrombin Patch versus Cellulose Gauze—Our Experience

Cited by 16 publications

References 16 publications

Measuring neck circumference to predict and detect haemorrhage following thyroid surgery. A case series and literature review

Measuring neck circumference to predict and detect haemorrhage following thyroid surgery. A case series and literature review

Is Intra-Articular Administration of Fibrinogen Effective in Postoperative Total Knee Arthroplasty Blood Loss? A Randomized Clinical Trial

Effect of fibrin vs cellulose based haemostatic agents with traditional haemostatic procedures in thyroid surgery

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