Haemophilic Pseudotumour of the Pelvis

Horwitz, H.; Simon, Neil; Bassen, Frank A.

doi:10.1259/0007-1285-32-373-51

Cited by 9 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From the reports by Ghormley and Clegg [9] and Horwitz et al. [38] it was assumed by some authors that long‐standing pseudotumours are reluctant to respond to radiation therapy and this treatment may better be reserved for recently developed lesions [28]; however, there is contrasting evidence that even lesions which had been present for years were successfully treated with radiotherapy [31,37]. The reverse is also true; Ahuja et al.…”

Section: Radiotherapymentioning

confidence: 99%

“…Not only did the authors report a broad range of radiation doses, they did also implement various fractionation protocols; dose fractions of 0.5-2 Gy were cited in different studies, which do not seem to affect the treatment outcome and complications related to radiotherapy (Table 1). From the reports by Ghormley and Clegg [9] and Horwitz et al [38] it was assumed by some authors that long-standing pseudotumours are reluctant to respond to radiation therapy and this treatment may better be reserved for recently developed lesions [28]; however, there is contrasting evidence that even lesions which had been present for years were successfully treated with radiotherapy [31,37]. The reverse is also true; Ahuja et al [34] and Echternacht et al [39] each reported one lesion of recent development in which radiotherapy failed to halt their progression.…”

Section: Referencesmentioning

confidence: 99%

See 1 more Smart Citation

Management of haemophilic pseudotumours with special emphasis on radiotherapy and arterial embolization

2009

View full text Add to dashboard Cite

The haemophilic pseudotumour is an expanding destructive haematoma, which is associated with a considerable amount of morbidity in haemophilic patients. Its prevention is paramount. In fact, this goal can be achieved by primary prophylaxis to avoid muscle haematomas and by adequate and long-term haematological treatment of muscle haematomas in case they appear. At the moment, surgical excision of pseudotumour is the preferred treatment by many authors. However, there are instances that surgical extraction of the lesion is not feasible. In such situations, radiotherapy and arterial embolization should be considered either alone or as an adjunct to surgery. Conservative management using a combination of radiotherapy and replacement therapy should be considered for treating haemophilic bone pseudotumours, which are located in the skull or in the distal parts of the limbs, especially in conditions where some impediments to surgical excision exist. In fact, the radiation should be delivered to the lesion site in small fragments of 2 Gy or less to a total dosage of 6-23.5 Gy, which is the most recommended radiation dosage, at the moment. Therapeutic arterial embolization of haemophilic pseudotumours should be considered in lesions of large size, especially in pseudotumours of pelvic region, as it may effectively reduce its size and decrease the risk of bleeding complications during surgery. Nevertheless, in view of its temporary effect, embolization may better be performed, as a preparatory procedure, at best about 2 weeks prior to surgery. This time lapse will allow for mass shrinkage but is insufficient for vessel restoration.

show abstract

Section: Radiotherapymentioning

confidence: 99%

Section: Referencesmentioning

confidence: 99%

Management of haemophilic pseudotumours with special emphasis on radiotherapy and arterial embolization

2009

View full text Add to dashboard Cite

show abstract

“…Abell and Bailey (1960) reviewed 17 cases of haemophilic pesudotumour from the literature, and Fraenkel, Taylor, and Richards (1959), using the term haemophilic blood cyst, discussed eight more; each paper contributed two case reports. Horwitz, Simon, andBassen (1959), Birk (1960), Crock and Boni (1960), Schwarz (1960), and Nelson and Mitchell (1962) have described further examples. The common feature seems to be bone involvement, usually of the ilium or femur.…”

Section: Case Reportmentioning

confidence: 99%

Haemophilic Pseudotumour after Fractured Femur

Harrison¹

1964

BMJ

View full text Add to dashboard Cite

Radiotherapy of pseudotumors of bone in hemophiliacs with circulating inhibitors to factor VIII

Castaneda

Parmley

Bozzini³

et al. 1991

American J Hematol

View full text Add to dashboard Cite

Pseudotumors of bone in two hemophiliacs with severe factor VIII deficiency and a high level of circulating inhibitors are reported. Both had favorable response to radiation therapy after unsuccessful treatment with factor concentrates and remain free of recurrence at 18-62 months. A review of the literature of cases in which radiotherapy has been used is presented. Radiotherapy in the treatment of pseudotumors of bone in hemophiliacs should be strongly considered, particularly if coagulation factor inhibitors are present.

show abstract

Haemophilic Pseudotumour of the Pelvis

Cited by 9 publications

References 2 publications

Management of haemophilic pseudotumours with special emphasis on radiotherapy and arterial embolization

Management of haemophilic pseudotumours with special emphasis on radiotherapy and arterial embolization

Haemophilic Pseudotumour after Fractured Femur

Radiotherapy of pseudotumors of bone in hemophiliacs with circulating inhibitors to factor VIII

Contact Info

Product

Resources

About