Haemolytic uraemic syndrome with acute oedematous pancreatitis

A case of hemolytic uremic syndrome and whole splenic infarction secondary to acute pancreatitis

“…A variety of proteases and cytokines, such as interleukin‐1 and tumor necrosis factor‐α, released during acute pancreatitis can directly and/or indirectly damage the endothelium and promote platelet aggregation, which may lead to HUS. The apparent reversibility of renal insufficiency following treatment with plasmapheresis, fresh frozen plasma infusions and hemodialysis has often been reported in patients with HUS secondary to acute pancreatitis 1–3 . In the present case, the renal function of the patient recovered to normal within 24 days after starting treatment for HUS.…”

Pancreatitis preceding acute episodes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: report of five patients with a systematic review of published reports

“…[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] Among these 16 patients, 13 were men, opposite to the gender disparity of TTP-HUS 25 but consistent with the greater frequency of acute pancreatitis among men. 43 The etiologies of the pancreatitis in these 16 patients were typical for acute pancreatitis among adults: 43,44 seven cases were related to chronic severe alcohol use, five to gallbladder disease, and four were idiopathic.…”