Haemoglobin H Disease in a Turkish Family

Özsoylu, Şînasi; Işık, Kutay

doi:10.1111/j.1600-0609.1973.tb00039.x

Cited by 4 publications

(1 citation statement)

References 24 publications

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“…We detected 198 patients with HbH disease when we searched articles from PubMed related to Turkish patients with HbH disease [ 10 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. When the results of our study were added to that number, we found 471 HbH cases to date from Turkey, and this number is fairly high ( Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

Hemoglobin H Disease in Turkey: Experience from Eight Centers

Ünal

Oktay²,

Acıpayam³

et al. 2016

Tjh

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The purpose of this study was to research the problem of hemoglobin H (HbH) disease, to reveal the distribution patterns among different health centers, and to emphasize the importance of this disease for Turkey. A total of 273 patients were included from 8 hemoglobinopathy centers. The Antakya Hemoglobinopathy Center reported 232 patients and the remaining 7 centers reported 41 patients. PubMed was also searched for published articles related to Turkish patients with HbH disease, and we found 16 articles involving a total of 198 HbH patients. Most of the patients were reported from Antakya; thus, special attention should be paid to this region. This is a preliminary study to investigate the extent of the problem of HbH disease and it emphasizes the need for hematology associations or the Ministry of Health to record all cases of HbH disease in Turkey.

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Section: Discussionmentioning

confidence: 99%

Hemoglobin H Disease in Turkey: Experience from Eight Centers

Ünal

Oktay²,

Acıpayam³

et al. 2016

Tjh

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Sickle‐Cell Anaemia in Turkey Evaluation of 97 Cases (with Parents' Findings)

Özsoylu

ALTINÖZd

1977

Scandinavian Journal of Haematology

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The haematological and clinical data in 97 sickle‐cell anaemia cases and haemato‐logical findings of their parents are reported. In spite of the low Hb values of the patients, they tolerated their anaemia and very rarely required blood transfusions. The Hb F levels of the patients were in general higher than African origin SS anaemia patients but lower than the Shiite Saudi Arabians. However, in most of the cases the concentration of Hb F did not seem to influence the Hb concentration of the patients. Serum iron was found unexpectedly decreased in 22 % of the patients. Osmotic fragility was found decreased in 100 % of the patients and in 83.5 % of the parents. The prevalence of G‐6‐PD deficiency was 21.2 % in male patients and 15.6 % in the parents.

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Haemoglobinopathy Survey in an Eti -Turk Village

Özsoylu¹,

Sahinoglu²

1975

Hum Hered

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Blood specimens were obtained from 281 inhabitants of an Eti-Turk village with a population of about 500. Starch gel (pH 8.6) and agar gel (pH 6.45) electrophoresis were performed in 279 of the specimens. Hb S was present in 105 partially interrelated persons (37.36%), three of whom had sickle-cell anaemia. Hb E was detected in 5 persons (1.79%), one of whom was a double heterozygote for Hb S and Hb E. One Hb S + α-thalassaemia and 7 Hb S with elevated Hb A’₂ combinations were found. The β-thalassaemia gene prevalence was 0.0377. Hb A₂ was found in 4 persons (1.42%), and Hb F was slightly increased in 37 (22.3%) persons with a normal haemoglobin picture. Erythrocyte G-6-PD deficiency was 10% among males.

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Haemoglobin H Disease in a Turkish Family

Cited by 4 publications

References 24 publications

Hemoglobin H Disease in Turkey: Experience from Eight Centers

Hemoglobin H Disease in Turkey: Experience from Eight Centers

Sickle‐Cell Anaemia in Turkey Evaluation of 97 Cases (with Parents' Findings)

Haemoglobinopathy Survey in an Eti -Turk Village

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