Haemodynamics of giant cerebral aneurysm: A comparison between the rigid-wall, one-way and two-way FSI models

Khe, A. K.; Cherevko, A. A.; Чупахин, А. П.; Bobkova, M S; Кривошапкин, А. Л.; Orlov, Kirill

doi:10.1088/1742-6596/722/1/012042

Cited by 15 publications

(8 citation statements)

References 6 publications

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“…Such study is associated with a whole range of problems since an investigation can be performed only when, during a destructive vascular surgery on the brain, the length of the donor artery allows cutting off a piece of sufficient size for research. The work [ 25 ] indicates the realism of the above-described prospects for using the technique, in which this technology, in fact, could already bring a specific result.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between the Strength Characteristics of Cerebral Aneurysm Walls with Their Status and Laser-Induced Fluorescence Data

et al. 2021

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Background: Cerebral aneurysms (CA) are a widespread vascular disease affecting 50 per 1000 population. The study of the influence of histological, morphological and hemodynamic factors on the status of the aneurysm has been the subject of many works. However, an accurate and generally accepted relationship has not yet been identified. Methods: In our work, the results of mechanical and spectroscopic measurements are considered. Total investigated 14 patients and 36 their samples of CA tissue. Results: The excitation–emission matrix of each specimen was evaluated, after which the strength characteristics of the samples were investigated. Conclusions: It has been shown that there is a statistically significant difference in the size of the peaks of two components, which characterizes the status of the aneurysms. In addition, a linear regression model has been built that describes the correlation of the magnitude of the ultimate strain and stress with the magnitude of the peaks of one of the components. The results of this study will serve as a basis for the non-invasive determination of the strength characteristics of the cerebral tissue aneurysms and determination of their status.

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Section: Discussionmentioning

confidence: 99%

The Relationship between the Strength Characteristics of Cerebral Aneurysm Walls with Their Status and Laser-Induced Fluorescence Data

et al. 2021

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“…The most pronounced nodal differences were noted for local WS and deformation, which were underestimated in one-way FSI. These local differences may be non-negligible in studies where local arterial wall distensions and stress concentrations are studied such as aneurysm models [110]. For the numerical modelling of the arterial wall, the importance of applying an appropriate pre-stress to the structural model is widely established in the literature [111].…”

Section: Figure 6: Node-wise Comparison Of One-way and Two-way Fsi Re...mentioning

confidence: 99%

Fluid-Structure Interactions of Peripheral Arteries Using a Coupledin silicoandin vitroApproach

Schoenborn

Lorenz²,

Kuo³

et al. 2023

Preprint

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Vascular compliance is considered both a cause and a consequence of cardiovascular disease and a significant factor in the mid- and long-term patency of vascular grafts. However, the biomechanical effects of localised changes in compliance, such as during plaque development or after bypass grafting and stenting, cannot be satisfactorily studied with the available medical imaging technologies or surgical simulation materials. To address this unmet need, we developed a coupled silico-vitro platform which allows for the validation of numerical fluid-structure interaction (FSI) results as a numerical model and physical prototype. This numerical one-way and two-way FSI study is based on a three-dimensional computer model of an idealised femoral artery which is validated against patient measurements derived from the literature. The numerical results are then compared with experimental values collected from compliant arterial phantoms. Phantoms within a compliance range of 1.4 - 68.0%/100mmHg were fabricated via additive manufacturing and silicone casting, then mechanically characterised via ring tensile testing and optical analysis under direct pressurisation with differences in measured compliance ranging between 10 - 20% for the two methods. One-way FSI coupling underestimated arterial wall compliance by up to 14.71% compared to two-way FSI modelling. Overall, Smooth-On Solaris matched the compliance range of the numerical and in vivo patient models most closely out of the tested silicone materials. Our approach is promising for vascular applications where mechanical compliance is especially important, such as the study of diseases which commonly affect arterial wall stiffness, such as atherosclerosis, and the model-based design, surgical training, and optimisation of vascular prostheses.

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“…All this makes the use of such models quite inefficient; in addition, it requires the use of significant amount of computing resources. Although there is a suitable area for the application of such models: threedimensional analysis of blood circulation parameters in the aorta [18], in the main cerebral vessels [19], in the aneurysm [20]. Summarizing all the above, it can be argued that the proposed models require the use of rather…”

Section: Problem Statementmentioning

confidence: 99%

Mathematical Model for the Investigation of Human Organism Functional Self-organisation

Aralova

Klyuchko²,

Mashkin³

et al. 2021

ECS

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Mathematical modeling of processes occurring in living organism is convenient and reliable tool for the understanding of mechanisms of human organism self-organization, interaction and inter-influence of its functional systems. The simulations of processes occurring in organism during various extreme perturbations at mathematical models allow us to study the parameters of self-organization in these perturbations at the level unavailable currently for modern invasive methods as well as to predict the organism steady state at given level of perturbing effects. The objects of study were the reactions of respiratory and blood circulatory systems, because these systems, according to the theory of adaptation by F. Meerson, are the most sensitive to the disturbing effects of environment. The paper provides a brief overview of mathematical models of respiratory and blood circulatory system; in the construction of these models rather complex mathematical apparatus was used and, accordingly, the implementation of which requires significant computational resources. The mathematical model of the functional respiratory system was proposed; it is based on the principle of the main function of respiratory system realization and takes into account conflict situations that occur in organism during this function fulfillment. This conflict happens between the governing and executive self-regulatory organism organs as well as between the different tissues groups in their fight for the oxygen. Mathematically, the model is a system of ordinary nonlinear differential equations that describe the transport and mass transfer of respiratory gases in all structural parts of respiratory system. The task of control of gases dynamics in organism was solved using the principle of Pontryagin maximum.

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Haemodynamics of giant cerebral aneurysm: A comparison between the rigid-wall, one-way and two-way FSI models

Cited by 15 publications

References 6 publications

The Relationship between the Strength Characteristics of Cerebral Aneurysm Walls with Their Status and Laser-Induced Fluorescence Data

The Relationship between the Strength Characteristics of Cerebral Aneurysm Walls with Their Status and Laser-Induced Fluorescence Data

Fluid-Structure Interactions of Peripheral Arteries Using a Coupledin silicoandin vitroApproach

Mathematical Model for the Investigation of Human Organism Functional Self-organisation

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