Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease

Nistor, Ionuţ; Palmer, Suetonia C.; Craig, Jonathan C.; Saglimbene, Valeria; Vecchio, Mariacristina; Covic, Adrian; Strippoli, Giovanni F.M.

doi:10.1002/14651858.cd006258.pub2

Cited by 76 publications

(69 citation statements)

References 149 publications

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“…The Cochrane Review undertaken by Nistor et al (2015) supports this conclusion and could only find statistically significant evidence for patient improvement with respect to reduced mortality from CVD for patients receiving HDF. These findings have been replicated in the more recent large scale cohort study of DOPPS data completed by Locatelli et al (2017).…”

Section: Resultsmentioning

confidence: 95%

“…The ESHOL Study concluded that HDF reduced all-cause mortality when compared to conventional HD treatment. Nistor et al (2015) undertook a Cochrane review of twenty separate HDF studies (randomised control trials (RCTs) and quasi-RCTs) comprising a total of nearly 3500 patients. The ESHOL Study cited above was included in the review.…”

Section: Hdf Evidence Basementioning

confidence: 99%

“…The Nistor et al (2015) review found that HDF did result in a significant reduction in death from cardiovascular causes when compared to HD, which they quantified in terms of HDF potentially 4/2 preventing 25 cardiovascular deaths for every 1000 patients treated when compared to HD. However, when the reviewers looked at all-cause mortality they found no significant advantage for HDF over HD therapy.…”

Section: Hdf Evidence Basementioning

confidence: 99%

See 2 more Smart Citations

A review of the evidence for the use of haemodiafiltration

Dainton

2017

Journal of Kidney Care

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Most patients with end stage renal disease (ESRD) are supported with maintenance haemodialysis (HD) and this has been the case for many years. Recent improvements in water quality have led to the increased use of high-flux HD and more recently of online-haemodiafiltration (HDF). HDF has been promoted by some clinicians and by renal industry as potentially offering improved clinical and quality of life outcomes for patients over conventional HD. However, despite such benefits making theoretical sense very few studies of the use of HDF as compared to HD (especially high-flux HD) have been able to demonstrate any significant benefit for the therapy. This article reviews the most recent research that has compared HDF and HD and has identified that the evidence for the benefit of HDF remains elusive. This article, therefore, concludes that there is currently still not sufficient evidence from the research to support the contention that HDF confers benefits to patients over conventional HD and thereby no compelling evidence to justify its widespread use as a preferred form of treatment.

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Section: Resultsmentioning

confidence: 95%

Section: Hdf Evidence Basementioning

confidence: 99%

Section: Hdf Evidence Basementioning

confidence: 99%

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A review of the evidence for the use of haemodiafiltration

Dainton

2017

Journal of Kidney Care

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“…However, numerous studies have struggled to show conclusive benefit to all patients from this treatment [3] .…”

Section: Introductionmentioning

confidence: 99%

The Rationale for Expanded Hemodialysis Therapy (HDx)

Hutchison

Wolley

2017

Expanded Hemodialysis: Innovative Clinical Approach in Dialysis

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As dialysis membrane technologies have advanced, the ability to clear increasing numbers of uremic toxins has occurred. To date, however, the class of uremic toxins known as large middle-molecules has been classified as "difficult to remove." Expanded hemodialysis utilizes a new generation of high-retention-onset hemodialysis membranes; these membranes provide the ability to remove large middle-molecules effectively for the first time, without significant albumin loss. In this review, we evaluate the removal of large middlemolecules by the new high-retention-onset membranes, the clinical relevance of these molecules, and how expanded hemodialysis can be prescribed.

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“…Através dessa membrana, ocorrem trocas por difusão (cerca de 90%), além de poder ocorrer filtração e trocas por convecção. [1][2][3][4][5] O circuito extracorpóreo é suportado por um equipamento de complexidade variável, que prepara, aquece, avalia e fornece a solução de diálise, impulsiona o sangue com uma bomba e monitora uma série de parâmetros do processo (pressão do sangue, pressão do dialisato, fluxo do sangue, fluxo do dialisato, concentração do dialisato, temperatura, presença de ar no compartimento sanguíneo, presença de sangue no dialisato, volume de ultrafiltração). Uma série de alarmes ligados ao sistema de monitorização evita acidentes, tornando o processo mais seguro.…”

Section: Introductionunclassified

Sintomas e complicações agudas relacionadas com a hemodiálise

Deus

Hoerb

Zanon

et al. 2015

Rev Epidemiol Control Infect

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Exceto onde especificado diferentemente, a matéria publicada neste periódico é licenciada sob forma de uma licença Creative Commons -Atribuição 4. brio hídrico e eletrolítico e alterações hemodinâmicas, com destaque para cefaleia. Backgound and Objectives:Chronic Kidney Disease and the number of patients on renal replacement therapies have become more frequent in recent decades. Even with new technologies used in hemodialysis, which result in greater patient safety, acute symptoms and complications after the procedure may still occur. Recognizing these complications and knowing how to manage them is crucial to ensure a better quality of life for these patients.Content: This is a literature search on symptoms related to hemodialysis, carried out in electronic databases:Periodicals CAPES (Coordination of Higher Education Personnel Training, Brazil), Scientific Electronic Library Online -SciELO, LILACS and Pubmed, from which 30 articles were selected on the main complications observed and described during the course of hemodialysis. Conclusion: There was a prevalence of symptoms related to fluid and electrolyte imbalance and hemodynamic changes, especially headache. RESUMO ABSTRACT ARTIGO DE REVISÃOSintomas e complicações agudas relacionadas com a hemodiálise

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Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease

Cited by 76 publications

References 149 publications

A review of the evidence for the use of haemodiafiltration

A review of the evidence for the use of haemodiafiltration

The Rationale for Expanded Hemodialysis Therapy (HDx)

Sintomas e complicações agudas relacionadas com a hemodiálise

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