Haematopoietic Enhancing Effect of Ethanolic Seed Extract of Citrullus lanatus (Watermelon) on Bone Marrow of Wistar Rats

Finbarrs-Bello, Elizabeth; Nto, N; Ikele, Ikenna Theophilus; Sani, M F Halaji; Atuadu, Vivian

doi:10.9734/ejmp/2016/30452

Cited by 5 publications

(5 citation statements)

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“…The identified functional groups include hydroxyl groups (OH), amine groups (N-H), aliphatic hydrocarbon groups (C-H), carbonyl groups (C=O), carbon-nitrogen bonds (C-N), and a sulfoxide group (S=O). These findings are consistent with previous studies [21], [22], [23], confirming the reliability of FTIR analysis. The observed peaks at specific frequencies provided valuable insights into https://doi.org/10.53982/ajerd.2023.0602.01-j Keke et al Volume 6,Issue 2 https://doi.org/10.53982/ajerd 7 chemical compounds present in watermelon sampled oil.…”

Section: Discussion Of Ftir Analysis Of Watermelon (Citrillus Lanatus...supporting

confidence: 93%

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Keke,

Okpo,

Anakpoha

2023

AJERD

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This study focuses on employing solvent extraction to extract and characterize watermelon (Citrullus lanatus) seed oil. The physicochemical properties of the oil were investigated to assess its potential applications in the food, cosmetic, and pharmaceutical industries. The extraction process yielded an oil content of 43%. The oil exhibited a pH value of 4.02, refractive index of 1.452 at 25 °C, and specific gravity of 0.934 at 15 °C. The boiling point, cloud point, flash point, and melting point of oil were determined as 326 °C, 7.3 °C, 289 °C, and 2 °C, respectively. The oil's viscosity was measured as 0.04072 Pa.s, and it demonstrated a non-sooty flame nature and solubility in ether. The free fatty acid contents and acid value were determined at 3.339 % and 6.678 mg KOH/g, respectively. The saponification value (S.V) and iodine value (I.V.) were 147.6315 mg/KOH/g and 88.526 mg Iodine/g, respectively. Additionally, peroxide value was 16.40 meq peroxide/g, and the oil exhibited a congealing temperature range of -14 °C to 22 °C. The oil's retention factor during chromatography was determined as 1.6 cm. Fourier-transform infrared (FTIR) analysis revealed the presence of functional groups such as hydroxyl, amine, aliphatic hydrocarbon, carbonyl, carbon-nitrogen bond, and sulfoxide groups in the oil. These findings suggest that the presence of functional groups, such as hydroxyl, amine, aliphatic hydrocarbon, carbonyl, carbon-nitrogen bond, and sulfoxide groups in watermelon oil, indicate its potential suitability for a wide range of applications in the food, cosmetic, and pharmaceutical industries.

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Section: Discussion Of Ftir Analysis Of Watermelon (Citrillus Lanatus...supporting

confidence: 93%

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Keke,

Okpo,

Anakpoha

2023

AJERD

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“…Haematopoietic potentials of African medicinal plants such as Telferia occidentalis, Citrillus lanatus spinach and wheatgrass have been reported [17]. Phytochemicals such as beta-carotene, lutein, saponin and quercetin have been reported to be responsible for the observed haematopoietic potentials of these plants.…”

Section: Discussionmentioning

confidence: 99%

Haematopoietic Potential of Jatropha tanjorensis Leaf Extract in <i>Plasmodium berghi-berghi</i> Infected Mice Treated with <i>Hippocratea africana</i> Root Bark Extract

Ndem¹,

Bassey²,

Effiong³

et al. 2019

JDMP

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The haematopoietic potential of Jatropha tanjorensis leaf extract in Plasmodium berghi-berghi infected mice treated with Hippocratea africana root bark extract was investigated. Thirty (21) adult mice weighing 27-33g were divided into seven (7) groups with three (3) animals in each group. Group 1 served as normal control while Groups 2-7 were parasitized with Plasmodium berghi-berghi and Group 2 was the test control (parasitized and untreated) group. Group 3 was administered 8mg/kg bw of artemether-lumefantrine for 3 days. Group 4 and 5 received daily, 200mg/kg bw and 300mg/kg bw of extracts of Hippocratea africana and Jatropha tanjorensis respectively for 4 days. Group 6 received 8mg/kg bw of artemether-lumefantrine for 3 days followed with 300mg/kg bw of Jatropha tanjorensis leaf extract for 4 days. Group 7 was treated with 200mg/kg bw of Hippocratea africana root extract for 4 days followed by 300mg/kg bw of Jatropha tanjorensis leaf extract for 4 days. Significant anti-plasmodial activity was observed with artemether-lumefantrine and Hippocratea africana root bark extract administration. Plasmodium berghi-berghi infection induced alterations in haematological indices such as decreased RBC count, platelet count, haemoglobin concentration and heamatocrit and increased WBC count. Administration of Jatropha tanjorensis leaf extract showed improved haematological indices particularly in the red blood cell counts and haemoglobin concentration. Jatropha tanjorensis has haematopoietic activity in Plasmodium berghi-berghi infected mice treated Hippocratea africana root bark extract.

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“…The major lipids found in the seed include: polyunsaturated fatty acids such a s linoleic acid, oleic acid, palmitic and stearic acid [7]. In our previous studies, citrullus lanatus extract exhibited enhanced haematopoietic activity of the bone marrow, immunoreactivity to the neurofilament in the hippocampus and total serum proteins in rats given same diets [8,9]. These implicated citrullus lanatus for the normal function of the body particularly the brain [10].…”

Section: Introductionmentioning

confidence: 89%

Cortical Synaptophysin Immunoreactivities of Citrullus Lanatus Extract, Soya Bean Oil and Omega H3

2019

IJBPAS

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The distribution of immuno reactivity of cortical synaptophysin was examined in the cerebrum of adult rats treated with seed extract of Citrullus lanatus, Omega H 3 and soybean oil. Twenty (20) adult wistar rats of average weights 150g were used. The rats were randomly divided into 5 groups of 4 rats per group. Group A served as control, groups B and C received 100mg/kg and 200mg/kg of Citrullus lanatus ethanolic seed extract respectively, while groups D and E received 300 mg/kg of Omega H3 and 5ml Soybean oil for two weeks respectively. Serum lipids were estimated biochemically and statistically analyzed, Result was presented asmean ± standard deviation, P< 0.05 was considered statistically significant. The cerebrum was dissected, fixed, processed and stained for synaptophysin. The result shows Soya bean oil significantly increased total serum cholesterol and serum Low Density Lipoprotein compared with the seed extracts of C. lanatus and omega H 3 . Ethanolic seed extract of C. lanatus, Omega H 3 and Soya bean oil had no significant effect on serum triglyceride. The low dose of the seed extract and Soya bean oil significantly decreased High Density Lipoprotein. In conclusion, the seed extracts of C. lanatus shows dose dependant

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Haematopoietic Enhancing Effect of Ethanolic Seed Extract of Citrullus lanatus (Watermelon) on Bone Marrow of Wistar Rats

Cited by 5 publications

References 0 publications

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Haematopoietic Potential of Jatropha tanjorensis Leaf Extract in <i>Plasmodium berghi-berghi</i> Infected Mice Treated with <i>Hippocratea africana</i> Root Bark Extract

Cortical Synaptophysin Immunoreactivities of Citrullus Lanatus Extract, Soya Bean Oil and Omega H3

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Haematopoietic Enhancing Effect of Ethanolic Seed Extract of Citrullus lanatus (Watermelon) on Bone Marrow of Wistar Rats

Cited by 5 publications

References 0 publications

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Extraction and Characterization of Watermelon (Citrullus lanatus) Seed Oil

Haematopoietic Potential of Jatropha tanjorensis Leaf Extract in &lt;i&gt;Plasmodium berghi-berghi&lt;/i&gt; Infected Mice Treated with &lt;i&gt;Hippocratea africana&lt;/i&gt; Root Bark Extract

Cortical Synaptophysin Immunoreactivities of Citrullus Lanatus Extract, Soya Bean Oil and Omega H3

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Haematopoietic Potential of Jatropha tanjorensis Leaf Extract in <i>Plasmodium berghi-berghi</i> Infected Mice Treated with <i>Hippocratea africana</i> Root Bark Extract