Haematology in sub-Saharan Africa: advances and opportunities in health care, education, and research

Makani, Julie; Moshi, Grace

doi:10.1016/s2352-3026(21)00275-1

Cited by 3 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sickle cell anaemia or the sickle cell trait was suspected in 13% pregnant women highlighting a crucial need to understand the burden of SCD in the country. Novel, rapid, inexpensive, and sensitive immunoassay-based point-of-care tests kits, found to have high sensitivity and speci city in sub-Saharan African settings should be available in STP for neonate screening programmes [24,45,46].…”

Section: Discussionmentioning

confidence: 99%

Antenatal Care in Sao Tome and Principe: Beyond the Number of Visits

Vasconcelos

Sousa

Bandeira

et al. 2022

Preprint

View full text Add to dashboard Cite

Background: Newborn mortality in Sao Tome and Principe (STP) is overwhelmingly high and the antenatal healthcare (ANC) is one of the strategies to achieve its reduction. This study aimed to know which antenatal screenings are done in STP and which antenatal problems are detected. Methods: A retrospective study in which 518 pregnant women antenatal cards were reviewed between July 2016 and November 2018. Information analysed included clinical factors, laboratory tests, ultrasounds, results, and treatment. Results: Mothers’ mean age was 26.6 (SD=7.1) years old. At least one ANC visit occurred in 98.6% pregnant women and 38.7% had 8 or more. Regarding laboratory screenings, blood group was done in 64.4%, haemoglobin tested in 62.5% (first trimester) and in 29.3% (second trimester) and, urine once in 57.1% and twice in 12.2%. Antenatal problems identified in the pregnant women studied were: i) a RhD-negative phenotype (5.8%); 2) anaemia 1st trimester (36.4%) and 2nd trimester (35.5%); 3) bacteriuria (43.2%); 4) intestinal parasites (55.5%); 5) sickle cell solubility test positive (13%). Overall, 161 (53.7%) out of the 300 ultrasounds were done before the 20th week. Conclusion: In Sao Tome and Principe many pregnant women do not have access to the full spectrum of ANC recommended screenings. Maternal anaemia and bacteriuria are the main health problems that should be urgently addressed to prevent newborn morbidity and mortality in the country. Other preventive interventions as anthelmintic drugs should be debated as intestinal parasites were diagnosed in more than half of the women. Alloimmunization to RhD is also a concern due to the unaffordability of anti-D immunoglobulin in the country.

show abstract

Section: Discussionmentioning

confidence: 99%

Antenatal Care in Sao Tome and Principe: Beyond the Number of Visits

Vasconcelos

Sousa

Bandeira

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Thus, the sub-Saharan African scientific literature is comparatively replete with research and data on lymphoid malignancies around the continent. There are currently many organisations supporting lymphoma research and treatment in sub-Saharan Africa, including several national, regional, and international consortia, collaborations, and partnerships [9,10].…”

mentioning

confidence: 99%

The paucity of epidemiological data and challenges of diagnosis in myeloid neoplasms in sub‐Saharan Africa: A call for action?

Yusuf,

Ibrahim

2023

Tropical Med Int Health

View full text Add to dashboard Cite

The global burden of non-communicable diseases (NCDs) is substantial. In 2019, NCDs resulted in over 1620 million disability-adjusted life years (DALYs) and 42 million deaths, with 77% of mortality in low-and middle-income countries (LIMCs) [1]. Neoplasms ranked fourth in the global burden of NDCs, surpassed only by cardiovascular, respiratory, and injuries, with 24.5 million incident cases and 9.6 million deaths due to cancer worldwide in 2017 [2]. Of these, neoplasms of the haematopoietic system constitute nearly 10% of all malignancies in sub-Saharan Africa, resulting in significant morbidity and mortality [3]. The number of new cases of haematological malignancies in this region is estimated to increase by 70% by the year 2030 [3,4]. According to the Global Burden of Disease Cancer Collaboration report that covered 2007 to 2017 [5], the global incidence rates of all cancers increased by 33.4%; chronic lymphocytic leukaemia increased by 40.5%, non-Hodgkin Lymphoma by 38.8%, multiple myeloma by 37.6%, acute lymphoblastic leukaemia by 29.3%, acute myeloid leukaemia by 23.2%, Hodgkin lymphoma by 15.2%, chronic myeloid leukaemia by 4.3% and other leukaemias by 8.9%.The 2001 World Health Organization (WHO) classification of haematopoietic and lymphoid neoplasms [6], with its subsequent editions and revisions, provided the first classification for haematological malignancies that incorporated clinical, genetic, immunophenotypic, as well as morphological information into a single scheme. In the latest revision in 2022 [7], neoplasms of the haematopoietic system were Sustainable Development Goal: Ensure Healthy lives and Promote Well-Being for All at All Ages.

show abstract

Patient Safety Efforts in Tanzania: A Rapid Review of Two-Decades Efforts (2002-2022) to Inform Interventions towards Attainment of 2030 Targets

Hokororo¹,

Bahegwa²,

Ngowi³

et al. 2022

AID

View full text Add to dashboard Cite

Introduction: The need to address the problem of patient safety has been a focus of World Health Assembly (WHA) meetings of 2002, 2019 and 2021. The 2019 WHA Resolution urged the Member States to take action on patient safety. We aimed to review patient safety efforts in Tanzania from 2002 to 2022 to inform improvement efforts towards the 2030 target. Methods: A rapid literature review was conducted between January 2002 and April 2022.We searched Google, PubMed and PubMed Central in April and May 2022 using the following search terms: PubMed-"patient safety Tanzania", "blood safety in Tanzania", "safe surgery Tanzania", and "healthcare-associated infections Tanzania"; Google-"blood safety in Tanzania", injection safety in Tanzania", "infection prevention and control", "radiation safety in health facilities in Tanzania"; and PubMed Central-"injection safety in Tanzania. Results: The search identified 4160 articles, of which 4053 were removed in initial screening; 21 were duplicates, giving 86 relevant articles for full screening. Of the 86 articles, 04 were removed after the full screening, hence remaining with 82 articles. Among the 82 eligible articles, 27 are on IPC, 26 on safe surgery, 12 on blood safety, 07 on radiation safety, 06 on injection safety, and 02 on medication safety. One article was relevant to-blood safety, IPC and injection safety; and one article was relevant to-IPC and injection

show abstract

Haematology in sub-Saharan Africa: advances and opportunities in health care, education, and research

Cited by 3 publications

References 10 publications

Antenatal Care in Sao Tome and Principe: Beyond the Number of Visits

Antenatal Care in Sao Tome and Principe: Beyond the Number of Visits

The paucity of epidemiological data and challenges of diagnosis in myeloid neoplasms in sub‐Saharan Africa: A call for action?

Patient Safety Efforts in Tanzania: A Rapid Review of Two-Decades Efforts (2002-2022) to Inform Interventions towards Attainment of 2030 Targets

Contact Info

Product

Resources

About