Haematological profile of healthy pregnant women in Ibadan, South-western Nigeria

Akingbola, Titilola S.; Adewole, Isaac F.; Adesina, Olufisayo Adeyemi; Afolabi, Kayode; Fehintola, F. A.; Bamgboye, E. A.; Aken'Ova, Y A; Shokunbi, Wuraola A.; Anwo, J. A.; Nwegbu, Maxwell

doi:10.1080/01443610600963770

Cited by 41 publications

(42 citation statements)

References 12 publications

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“…Still in agreement with our finding was a study by Akingbola et al [10], from Ibadan South-west Nigeria, that found a significantly higher platelet counts in their non-pregnant women compared to the pregnant women. Their results of Hb and WBC in pregnancy were also consistent with ours.…”

Section: Discussionsupporting

confidence: 81%

Haematological Indices of Nigerian Pregnant Women

Oa¹,

Oa²,

Mm³

2017

J Blood Lymph

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Haematological profile to a large extent, reflects the overall well-being or otherwise of an individual. Anaemia, thrombocytopaenia and leucocytosis are among the most common changes observed in the haematological parameters of pregnant women. Paucity of documented reference values for pregnant women from this region necessitated this study, considering the importance of these parameters, the potential implication of its wrong interpretation and application and their effects on pregnancy and its outcome. A total of 253 women, aged 15-50 years were recruited. Two hundred and eleven of them were pregnant and 42 were non pregnant control. Assessment of some key haematological parameters showed higher WBC and ANC and lower platelets, Hb and ALC in the pregnant compared to the non-pregnant women (p<0.05). It also showed higher WBC and ANC and lower platelets and haemoglobin concentration with increasing trimester (p<0.05).

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Section: Discussionsupporting

confidence: 81%

Haematological Indices of Nigerian Pregnant Women

Oa¹,

Oa²,

Mm³

2017

J Blood Lymph

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“…Similar results were demonsterated by Akinbami et al, [5], who found that a progressive decline in Hb concentration from the first to the third trimester. These findings corroborate those of a similar study undertaken in Ibadan, south-western Nigeria, by Akingbola et al [24] in 2006, which reported exactly the same pattern. The progressive decline in Hb concentration from the first to third trimester may be due to an increased demand for iron as pregnancy progresses [5].…”

Section: Discussionsupporting

confidence: 83%

“…The increase observed in WBC count from the first to third trimester in this study is consistent with the findings of Akinbami et al, [5], Onwukeme and Uguru [11], and Akingbola et al, [24]. The increase is primarily due to an increase in neutrophils and may represent a response to stress due to redistribution of the WBCs between the marginal and circulating pools [5,33].…”

Section: Discussionsupporting

confidence: 82%

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Haematological Parameters in Pregnant Women Attended Antenatal Care at Sabratha Teaching Hospital in Northwest, Libya

Azab¹

2017

AJLM

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Abstract:The aim of this study was to evaluate the values of hematological parameters at different trimesters of pregnancy in pregnant women who attended antenatal care at Sabratha Teaching Hospital, Northwest Libya. This cross-sectional survey included consecutive pregnant women who attended the obstetrical department in Sabratha Teaching Hospital for prenatal booking. This study was carried out over period of 6 month from April 2016 to September 2016. The study involved 120 pregnant women as the study group and 40 non-pregnant women as control. The study pregnant women were between the ages of 18 to 45 years. 5 ml of venous blood samples were taken from each pregnant woman in K 3 -EDTA tubes for the haematological examinations. The analysis of haematological indices was done using automated hematological analyzer. The obtained results showed that the mean age of pregnant women was 30 years ± 5.8 SD, 48.4% of pregnant women were between 21-30 years old, 40.8% were at age between 31-40 years. The most prevalent blood group in pregnant women was group O, 47.5%; followed by blood group A, 28.3%; blood group B, 17.5% and blood group AB, 6.7%. 15.8% of the pregnant women were observed to lack Rh antigen in their blood. Highly significance decrease in Hb, Hct, MCH, MCHC, lymphocytes%, RBCs and blood platelets count and significant decrease in MCV as compared with non pregnant women. On the other hand, highly significance increased in WBCs count, and neutrophils % of pregnant women compared with non pregnant women. A progressive decline in Hb concentration and haematocrite values from the first to third trimester was observed. The mean corpuscular volume was significantly decreased in the second trimester. The values of MCH showed highly significant decrease in the second and third trimester, and MCHC decreased significantly in the first trimester. WBC count and neutrophils % showed highly significant increase from the first to the third trimester. Lymphocytes % were highly significant decreased from the first to the third trimester. Mixed percentage of leukocytes (eosinophil, basophil and monocytes) decreased significantly in the third trimester. Platelets count exhibited a highly significant decrease in the second and third trimesters, and a significantly decrease in the first trimester. It can be concluded that a significant changes in the haematological parameters at different trimesters of pregnancy in pregnant women. So it is essential to monitor and manage these parameters during pregnancy.

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“…Furthermore, massive and fatal obstetric haemorrhages occur in 3 to 5% of deliveries and in 30 to 50 per 100,000 deliveries, transfusion of blood products is required [4]. Hemorrhage during labour, delivery, pregnancy and postpartum accounts for 34% of maternal deaths in West Africa [5] and the overall outcome is more severe against a backdrop of severe anaemia in pregnancy and possibly a poor marrow reserve [6]. Quite a lot of these deaths in developing nations are preventable, as demonstrated by an audit of five hospitals in Senegal-48% of deaths were rated avoidable and 25% were considered probably avoidable.…”

Section: Introductionmentioning

confidence: 99%

Obstetric Emergencies and Transfusion Needs in a Nigerian Hospital

Ts¹,

Bello²

2016

HTIJ

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IBlood transfusion plays a significant role as a life-saving practice in emergency obstetrics and it is one of the essential components of comprehensive emergency obstetric care yielding a reduction in maternal mortality. While transfusion is commonly used to combat anaemia in obstetric practice, the majority of patients receiving transfusion are given to otherwise healthy women in response to undiagnosed obstetric hemorrhage. This study explores the need and blood transfusion rate among obstetrics patients at the University College Hospital (UCH), Ibadan to provide insight into the rationale behind such practices. This is a retrospective study of transfused obstetrics patients at UCH between the year 2009 and 2014. Information was extracted from their medical records using a pro-forma. Data were entered and analysed using SPSS version 20.Of the 21,208 births and 27,019 antenatal admissions during the study period, 597 patients were transfused and 565 medical records were analysed. Among these 565 patients, about two-thirds 412 (72.9%) were un-booked patients. The transfusion rate was 2.2% and the commonest associated obstetrics complication requiring transfusion was anaemia (65.5%) while 184 (32.6%) were transfused because of postpartum hemorrhage. Other indications for transfusion were abruptio placentae, malaria and placenta previa. Patients who delivered via Caesarean Section (CS) had the highest transfusion rate of 62.4% and the estimated blood loss during delivery was significantly higher among the unbooked patients (P<0.01). More than two-thirds, 466 (82.5%) received whole blood while only 2 (0.4%) received cryoprecipitate. About one-third of patients received single unit-transfusions.Though the overall obstetric transfusion rate was lower than that of comparable facilities, the transfusion rate among patients receiving CS was markedly high. Additionally, the majority of transfused obstetric patients had complications resulting in anaemia, while hemorrhage propagated the second highest number of cases requiring transfusion.

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Haematological profile of healthy pregnant women in Ibadan, South-western Nigeria

Cited by 41 publications

References 12 publications

Haematological Indices of Nigerian Pregnant Women

Haematological Indices of Nigerian Pregnant Women

Haematological Parameters in Pregnant Women Attended Antenatal Care at Sabratha Teaching Hospital in Northwest, Libya

Obstetric Emergencies and Transfusion Needs in a Nigerian Hospital

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