Haematological Profile of Hb Adana Among High School Students in Northeast of Peninsular, Malaysia
Lee Miin Phoon,
Mat Jusoh Siti Asmaa,
Nur Atikah Zakaria
et al.
Abstract:Hb Adana is a non-deletional α-thalassaemia variant, due to mutations in α1- or α2-globin codon 59 (αCD59) that produce unstable α-globin. Clinical appearance can range from silent carrier to blood transfusion reliance, hepatosplenomegaly, skeletal deformities, and spinal cord compression. Despite the importance of Hb Adana inheritance, this Hb variant is challenging to study since molecular tests are scarce and routine diagnosis can be missed. This study explored the distribution of Hb Adana among local high … Show more
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