Haematological interventions for treating disseminated intravascular coagulation during pregnancy and postpartum

Martí‐Carvajal, Arturo J; Comunián‐Carrasco, Gabriella; Peña‐Martí, Guiomar E

doi:10.1002/14651858.cd008577

Cited by 4 publications

(5 citation statements)

References 21 publications

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“…Amniotic fluid embolism, preeclampsia/eclampsia, placental abruption and placenta praevia, intrauterine fetal demise, intrauterine infection, septic abortion, and acute fatty liver of pregnancy are associated with develop in DIC during pregnancy. 34 , 35 The most common intraocular structure involved in DIC is choroid. Occlusion of the choriocapillaris by a thrombus leads to disruption of the overlying retinal pigment epithelium, causing serous retinal detachment.…”

Section: Resultsmentioning

confidence: 99%

Ocular changes during pregnancy

Naderan

2018

Journal of Current Ophthalmology

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PurposeTo summarize available literature on physiologic and pathologic ocular changes during pregnancy.MethodsNarrative review of literature.ResultsOcular changes occur commonly during pregnancy. Although most of these are benign physiologic responses to the metabolic, hormonal, and immunologic modifications to adopt the gestational product, there is some serious pathology that may develop, exacerbate, or even resolve over the course of pregnancy which requires prompt diagnosis and management. The pathological eye conditions can be classified into preexisting pathologies and emerging ocular diseases. Regardless of the different mechanisms by which these ocular changes occur, the key point is the establishment of an effective perinatal screening program to monitor the new development or successive progression of these ocular abnormalities. Irrespective of the visual health status of the pregnant women, regular perinatal eye examination should be scheduled in order to assure continuous surveillance of healthy eyes. Treatment of pathologic ocular conditions or functionally disturbing benign changes relies on an appropriate patient selection.ConclusionsDiscriminating pathological eye disease from physiologic ocular changes is important in order to establish an individualized treatment or preventive plan and constitutes the mainstay of obstetric ophthalmology. This individualized approach should always weigh the ocular benefits of treatment to the mother against the potential harms to the fetus.

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Section: Resultsmentioning

confidence: 99%

Ocular changes during pregnancy

Naderan

2018

Journal of Current Ophthalmology

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“…While the transfusion of blood products and clotting factors is required in these patients to treat acute hemorrhage, these interventions must be balanced with the concern of precipitating acute thrombosis [ 1 , 5 , 9 , 10 , 21 ]. Microvascular thrombosis may be manifest clinically as pulmonary emboli, venous thromboembolism, stroke, or acute tubular necrosis (ATN) resulting in acute kidney injury.…”

Section: Discussionmentioning

confidence: 99%

To Clot or Not: HELLP Syndrome and Disseminated Intravascular Coagulation in an Eclamptic Patient with Intrauterine Fetal Demise

Walker

Bonavia

2020

Case Reports in Anesthesiology

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A 39-year-old G2P1001 female presented from an outside hospital following an eclamptic seizure in the setting of HELLP syndrome. This condition was complicated by intrauterine fetal demise and disseminated intravascular coagulation, which required an emergent cesarean section. We report the work-up and intraoperative and postoperative management of this complex patient with multiple medical needs. We focus on the hemostatic abnormalities in this patient and describe how our management would differ from that of a similar, nonpregnant patient.

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“…Disseminated Intravascular Coagulation (DIC) is known to be a complication of pregnancy secondary to common obstetric causes including: amniotic fluid embolism, intrauterine fetal demise (IUFD), preeclampsia/eclampsia, placental abruption, placenta praevia, septic abortion, intrauterine infection, and acute fatty liver of pregnancy [11,[35][36][37].…”

Section: Dicmentioning

confidence: 99%

“…Increased thrombus formation most commonly leads to vascular obstruction within the choroid, specifically the choriocapillaris. Occlusion within the choriocapillaris can cause serous retinal detachment (SRD) through the disruption of the overlying retinal pigment epithelium [35][36][37][38].…”

Section: Dicmentioning

confidence: 99%

Ophthalmic Complications and Ocular Changes in Pregnancy- A Review

Henderson¹

2016

OGIJ

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Haematological interventions for treating disseminated intravascular coagulation during pregnancy and postpartum

Cited by 4 publications

References 21 publications

Ocular changes during pregnancy

Ocular changes during pregnancy

To Clot or Not: HELLP Syndrome and Disseminated Intravascular Coagulation in an Eclamptic Patient with Intrauterine Fetal Demise

Ophthalmic Complications and Ocular Changes in Pregnancy- A Review

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