Haematological and serum biochemistry profile of the juvenile wild African giant rat (<i>Cricetomys gambianus</i>, Waterhouse – 1840) in Nsukka, South-Eastern Nigeria – a preliminary investigation

Igbokwe, Casmir Onwuaso; Agina, Onyinyechukwu Ada; Okoye, Chidozie Nwabuisi; Onoja, Remigus Ibe

doi:10.1080/09712119.2016.1141772

Cited by 11 publications

(9 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is a hystricognathous rodent that belongs to the family thryonomydae, believed to have originated from Africa (Sallam et al, 2011). The rodent is fossorial and spends its day in dark burrows but moves about at night in search of food (Obadiah et al, 2015;Igbokwe et al, 2017). The grasscutter is also considered as an agricultural pest as it is known to feed on crops such as sugarcane, wheat, maize, and cassava (Igado et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…The mammalian eye is the organ of sight comprising three tunics viz, the corneo-sclera, uvea and retina. The grasscutter has a rod-dominated retina (Lau & Linsenmeier, 2012) and has been reported to have poor eyesight (Igbokwe et al, 2017). It is said to be visually adapted for inferior nocturnal vision as a result of high corneal diameter to eye diameter ratio, scanty retinal ganglion cells, and absence of tapetum lucidum (Peter-Ajuzıe et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Morphological evaluation of the orbit and peri-ocular glands of the African grasscutter (Thryonomys swinderianus)

Peter-Ajuzie¹,

Nwaogu²

2022

Sokoto J. Vet. Sc.

View full text Add to dashboard Cite

The morphological features of the orbit and peri-ocular glands of the herbivorous African grasscutter were evaluated in this study. Heads of the rats were processed using the cold-water maceration technique, while the peri-ocular glands were obtained and processed for light microscopy using the conventional paraffin technique. The orbit was laterally located and associated with an enlarged maxillary infraorbital foramen. This orbital configuration imparted the grasscutter with a panoramic field of vision and a hystricomorphous improved masticatory ability. The Zeis and meibomian glands were located in the eyelid and showed holocrine histological features with myoepithelial cells surrounding their secretory acini. The gland of Moll was a simple coiled tubular gland that, together with the gland of Zeis, were associated with the palpebral cilia. The large harderian gland situated posterior to the eyeball was a lobulated compound exocrine gland whose secretory cells contained basally-displaced nuclei and foamy cytoplasm. The protruding glandular mass located adjacent to the rostral half of the upper eyelid, which we named the suprapalpebral gland had similar histological features as the harderian gland. These peri-ocular glands produced mainly mucoid and lipid secretions required for maintenance of structural and functional integrity of the cornea and eyelid. The qualitative and quantitative data from this study will be useful in the understanding of the biology of the African grasscutter and in the identification of orbital and peri-ocular glandular pathology in this species.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Morphological evaluation of the orbit and peri-ocular glands of the African grasscutter (Thryonomys swinderianus)

Peter-Ajuzie¹,

Nwaogu²

2022

Sokoto J. Vet. Sc.

View full text Add to dashboard Cite

show abstract

“…A. indica is an important item in the traditional medicinal practice in the area of study, according to Pallav et al, (2014) every part of the plant is claimed to posses some medicinal and insecticidal properties, but the seed is grossly underutilized (Schmutterer, 1990). Igbokwe (2017) opined that it is the presence of some biologically active principles like azdirachtin meliacin, gedunin, salanin, nimbin, valasin and their derivatives that confers the anti-inflammatory, anti-hyper glycemic, anti-ulcers, anti-malarial, antifungal, anti-bacterial, anti-oxidant, anti-mutargenic, and immunomodulatory properties of neem seed oil in ma mmalian models including anti-feedant, repellent, effect in insects (Ndodo, 2013).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of safety of Azdirachta indica seed oil on Albino rat through haematological and some antioxidants by the rotatable central composite design (RCCD) of the response surface methodology (RSM)

Phillippa¹,

G²,

Ukom³

2018

IJEAB

View full text Add to dashboard Cite

show abstract

“…They serve as exotic pets in Britain (Cooper, 2008). Though the rats are thought to have poor visual capability (Igbokwe et al, 2017), information on their ocular characteristics is scarce.…”

mentioning

confidence: 99%

Preliminary Anatomical Assessment of the Eye of the African Giant Rat (Cricetomys gambianus)

Peter-ajuzıe

Nwaogu

Ajaebili

2020

ASD

View full text Add to dashboard Cite

Eleven African giant rats were caught, bilaterally enucleated and the globes were routinely processed for light microscopy. Eye weight, vertical and horizontal corneal diameters, as well as vertical, horizontal and axial eye diameters were obtained from each globe. Observed external macroscopic ocular features were typical of mammalian eyes comprising cornea, sclera and attached extraocular muscles. The eye dimensions were however generally smaller than those of humans. The large mean corneal diameter to mean eye diameter ratio of 0.86 as well as the scanty retinal ganglion cells observed are associated with morphological adaptations for nocturnal vision. Pigments observed in the retinal epithelium suggests absence of tapetum lucidum, indicating a sub-optimal nocturnal visual capability. This study has provided scientific documentation of some ocular morphological characteristics of the giant rat and has shown that the eye of this species will be anatomically unsuitable for xenotransplantation in humans.

show abstract

Haematological and serum biochemistry profile of the juvenile wild African giant rat (Cricetomys gambianus, Waterhouse – 1840) in Nsukka, South-Eastern Nigeria – a preliminary investigation

Cited by 11 publications

References 23 publications

Morphological evaluation of the orbit and peri-ocular glands of the African grasscutter (Thryonomys swinderianus)

Morphological evaluation of the orbit and peri-ocular glands of the African grasscutter (Thryonomys swinderianus)

Evaluation of safety of Azdirachta indica seed oil on Albino rat through haematological and some antioxidants by the rotatable central composite design (RCCD) of the response surface methodology (RSM)

Preliminary Anatomical Assessment of the Eye of the African Giant Rat (Cricetomys gambianus)

Contact Info

Product

Resources

About