Haematinic evaluation of &lt;i&gt; Lauha bhasma&lt;/i&gt; and &lt;i&gt; Mandura bhasma&lt;/i&gt; on HgCl&lt;sub&gt; 2&lt;/sub&gt; -induced anemia in rats

Sarkar, Prasanta Kumar; Prajapati, PK; Ak, Choudhary; Shukla, VJ; Ravishankar, B

doi:10.4103/0250-474x.39435

Cited by 27 publications

(24 citation statements)

References 6 publications

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“…[26272829303132333435363738] Amalaki , due to Madhura Rasa (sweet taste) and Sheeta Virya (cold potency) reduces Pitta [2627] and thus breaks down the main factor in the pathogenesis of Pandu Roga . Further, it contains richest source of vitamin-C, which helps in the absorption of iron thus increases its bioavailability.…”

Section: Discussionmentioning

confidence: 99%

“…[3031] Lauha Bhasma , the oxide of iron has a direct impact on bodily iron. [32333435363738] Thus, the double fold increase in the Pitta aggravation (due to fertile age and Dauhrid ) in pregnancy, Dhatrilauha possesses many fold effectiveness in anemia (IDA). This is evidenced with the significant results obtained in the majority of parameters in this study.…”

Section: Discussionmentioning

confidence: 99%

“…[313233] Presence of ascorbic acid (vitamin C) in Amalaki has a significant effect on iron bioavailability from cereals and pulses in vitro . [34] Lauha Bhasma also has a significant hematinic and cytoprotective activity,[35] hemoglobin regeneration efficacy. [36]…”

Section: Methodsmentioning

confidence: 99%

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Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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Background:Anemia in pregnancy is multi-factorial. Iron deficiency anemia (IDA) is the most common one. Major cause is increased demand of iron during pregnancy. In Ayurveda, under Pandu-Roga the features of anemia are described. It is characterized by Vaivarnyata or Varnanasha (change/destruction in normal color of the body), a disorder of Pitta vitiation. Ayurvedic management is an effective way of curing anemia in general by a large number of Lauha preparations of which Dhatrilauha has been used widely for centuries.Aim:To evaluate the effect of Dhatrilauha in the management of IDA based on the scientific parameters among pregnant patients.Materials and Methods:A total of 58 cases were selected by simple randomized sampling method as per inclusion criteria of pregnant women between 4th and 7th months of pregnancy with a clinical diagnosis and laboratory confirmation of IDA. Dhatrilauha 500 mg in two divided doses after food with normal potable water were given for 45 days with three follow-ups, each of 15 days intervals. Final assessment was done after completion of 45 days and results were statistically analyzed by using Cochran's Q-test and Student's t-test.Results:Dhatrilauha showed statistically significant (P < 0.01) improvement in the majority of sign-symptoms and objective parameters such as weakness, fatigue, palpitation, effort intolerance, breathlessness, heartburn, pallor, constipation, hemoglobin, red blood cells (RBC), hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, RBC distribution width, mean platelet volume, serum iron, and total iron binding capacity.Conclusion:Dhatrilauha possesses many fold effectiveness in anemia (IDA), which was evidenced with the significant results obtained in the majority of parameters in this study.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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“…Lauha bhasma possesses significant hematinic and cytoprotective activity. 12 Lauha bhasma also has hemoglobin regeneration efficacy. As per Ayurveda, Triphala is antianemic and antioxidant.…”

Section: Probable Mode Of Action Of Therapymentioning

confidence: 99%

“…Lauha (iron) preparations are said to be effective in IDA. 12,13 Based on Ayurveda classics and previous studies conducted on IDA, Lauha preparations, such as Navayasa Churna are observed to be effective in IDA, due to its Pandughna (antianemic), Prinana (nourishing and replenishing), and Raktaprasadana (providing qualitative and quantitative excellence) properties. Traditionally, Navayasa Churna is successfully used by Ayurvedic physicians for the management of Pandu.…”

Section: Introductionmentioning

confidence: 99%

Clinical Efficacy and Safety ofNavayasa Churnain the Management of Iron Deficiency Anemia

Sk¹,

Sharma²,

Rajesh³

et al. 2017

Journal of Research in Ayurvedic Sciences

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Introduction: Iron deficiency anemia (IDA) is a condition where deficiency of iron in the body leads to reduction in the number of red blood cells (RBC). Even though IDA is an easily manageable condition with excellent outcome, it is observed that modern iron preparation often irritates gastric mucosa and causes adverse effects. In Ayurveda, IDA can be correlated with pandu based on symptomatic similarity. Navayasa Churna is an iron containing herbomineral preparation used for the management of Pandu. In this study, clinical efficacy and safety of Navayasa Churna has been evaluated in IDA.

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Presence and activities of carbonaceous nano-materials in Ayurvedic nano-medicine preparations

Sarkar

Wele

2022

Int Nano Lett

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Haematinic evaluation of <i> Lauha bhasma</i> and <i> Mandura bhasma</i> on HgCl<sub> 2</sub> -induced anemia in rats

Abstract: New Antihistaminic Agents: Synthesis and Evaluation of H1-Antihistaminic actions of 3-[(N,N-Dialkylamino)alkyl)-1,2,3,4-tetrahydro-(1H)-thioquinazolin-4(3H)-ones and Their oxo Analogues

Cited by 27 publications

References 6 publications

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Clinical Efficacy and Safety ofNavayasa Churnain the Management of Iron Deficiency Anemia

Presence and activities of carbonaceous nano-materials in Ayurvedic nano-medicine preparations

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