Habituation and migraine

Coppola, Gianluca; Pierelli, Francesco; Schoenen, Jean

doi:10.1016/j.nlm.2008.07.006

Cited by 185 publications

(188 citation statements)

References 88 publications

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“…Taken together, in contrast with the view expressed in some recent reviews (e.g. Brighina et al, 2009;Coppola et al, 2013a;Coppola et al, 2009;de Tommaso et al, 2014;Magis et al, 2013), the actual evidence suggests that lack of pattern VEP habituation cannot be considered a reliable finding in interictal migraine. In addition, we could neither reproduce lack of habituation with 3.0 rps and 16' checks in the present study, nor with 3.0 rps and 8' and 65' or 1.9 rps and 31' and 62' checks in previous studies (Omland et al, 2013;Sand et al, 2009;Sand et al, 2008).…”

Section: Habituation Measured By Visual Evoked Potentials In Migrainecontrasting

confidence: 78%

“…This interpretation is also used in the present study, although there are other possible explanations for the amplitude decrement (Omland et al, 2011). Some groups have reported that VEP amplitudes do not decline in migraineurs in the period between attacks (interictally) (Bednar et al, 2014;Coppola et al, 2009;Ozkul and Bozlar, 2002). Migraineurs may therefore lack habituation.…”

Section: Introductionmentioning

confidence: 62%

“…Several review articles state that migraineurs have a tendency to have lower first block VEP amplitude (Brighina et al, 2009;Coppola et al, 2009;Magis et al, 2013). As far as we know, only one study has reported lower first block amplitude in migraineurs (Afra et al, 1998).…”

Section: Visual Evoked Potential Amplitude In Migrainementioning

confidence: 99%

See 2 more Smart Citations

Visual evoked potentials in migraine: Is the “neurophysiological hallmark” concept still valid?

Omland

Uglem

Hagen

et al. 2016

Clinical Neurophysiology

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Please cite this article as: Omland, P.M., Uglem, M., Hagen, K., Linde, M., Tronvik, E., Sand, T., Visual evoked potentials in migraine: Is the "neurophysiological hallmark" concept still valid ?, Clinical Neurophysiology (2015), doi: http://dx.doi.org/10. 1016/j.clinph.2014.12.035 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. • Lack of VEP habituation is not a reliable "neurophysiological hallmark" in interictal migraine• Strict focus on methodology, including blinding during the recording and assessment of VEP, is important to avoid overestimation of effect sizes in future studies.2 Abstract Objective Lack of habituation is considered a neurophysiological hallmark of migraine. However, the results of visual evoked potential (VEP) studies have been discrepant, possibly because of different stimulation parameters and lack of blinding. Hence, there is a need for independent confirmation of lack of VEP habituation in migraine. In this blinded study we applied 16' checks to supplement our previous findings with 8', 31', 62' and 65' checks. MethodsVEPs in 41 interictal migraineurs and 30 controls were compared. VEPs were recorded in six blocks of 100 single responses. Linear N70-P100 amplitude change over blocks (habituation slope) was compared with an independent samples Student's t-test. ResultsAmplitude decline over blocks was observed in both groups. Habituation slope was not significantly different between controls (-0.43 ± 0.54 μV/block) and migraineurs (-0.29 ± 0.35 μV/block) (p = 0.33). ConclusionVEP habituation with 16' checks did not differ in migraineurs and controls. This is in agreement with previous findings with other stimulation parameters. It is therefore unlikely that use of different stimulation parameters could explain the discrepant results of previous studies. No studies that applied blinding during recording of VEP have found lack of habituation in migraineurs. SignificanceLack of VEP habituation cannot be considered a reliable neurophysiological hallmark in migraine.

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Section: Habituation Measured By Visual Evoked Potentials In Migrainecontrasting

confidence: 78%

Section: Introductionmentioning

confidence: 62%

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Visual evoked potentials in migraine: Is the “neurophysiological hallmark” concept still valid?

Omland

Uglem

Hagen

et al. 2016

Clinical Neurophysiology

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“…29 We can determine the change in habituation level over the migraine cycle, and the discourse of Coppola G. shows that the sensory cortices of migraineurs react excessively to repetitive but not to a small series of stimuli. 30 In conclusion, data against the concept of lack of habituation are considered a neurophysiological hallmark in migraine. [28][29][30][31] Most studies have suggested that high and adaptive disturbance of episodic cortical excitability may further affect the cognitive function.…”

Section: Migraine and Event-related Potentialmentioning

confidence: 98%

“…30 In conclusion, data against the concept of lack of habituation are considered a neurophysiological hallmark in migraine. [28][29][30][31] Most studies have suggested that high and adaptive disturbance of episodic cortical excitability may further affect the cognitive function. A particular study concluded that migraineurs exhibit abnormal implicit evaluative processing of visual stimuli.…”

Section: Migraine and Event-related Potentialmentioning

confidence: 98%

Recent progress in migraine and cognitive disorder

et al. 2017

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Migraine is a chronic neurovascular disease characterized by recurrent unilateral headache, which induces incapacity. At present, there are many methods to evaluate cognitive function, and the cognitive function scale is commonly used. Recently, event-related potentials, resting state functional magnetic resonance imaging and other new technologies have been widely used to assess the cognitive function of migraine patients because of their high temporal resolution and high spatial resolution. In this paper, we can overview that the research progress of the relationship between migraine and methods of evaluate cognitive function.

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