Habitual Response to Stress in Recovering Adolescent Anorexic Patients

Miller, Samantha; Erickson, Sarah J.; Branom, Christina; Steiner, Hans

doi:10.1007/s10578-008-0112-y

Cited by 21 publications

(23 citation statements)

References 21 publications

(41 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(), a lack of emotional awareness may occur. Moreover, in patients with EDs, whatever the state of starvation or the duration of illness, as suggested by Miller, Erickson, Branom, and Steiner (), Nandrino et al . () or Zonnevylle‐Bender et al .…”

Section: Discussionmentioning

confidence: 90%

Emotional differentiation and parental bonding in inpatients suffering from eating disorders

Rommel

Nandrino

Antoine

et al. 2012

British J Clinic Psychol

View full text Add to dashboard Cite

Inpatients with EDs do not present with deficits in personal emotional awareness despite their self-perception. AR patients showed deficits in the emotional awareness of others. In patients with EDs, perceived maternal bonding influenced the development of emotional awareness, and this influence was dependent on the type of ED. Psychotherapies that focus on maternal bonding and emotional communication within the family unit may enhance emotional awareness in patients with anorexia or subclinical eating pathologies as an alternative.

show abstract

Section: Discussionmentioning

confidence: 90%

Emotional differentiation and parental bonding in inpatients suffering from eating disorders

Rommel

Nandrino

Antoine

et al. 2012

British J Clinic Psychol

View full text Add to dashboard Cite

show abstract

“…Namely, that elevated expression of EPHX2 was observed in the paraventricular nucleus (PVN) of the thalamus is interesting in light of studies linking PVN function to food and water intake(52), weight gain in rats(53) and stress response. (54) Additionally, abnormal expression in sexually dimorphic regions such as corpus callosum and hippocampus may also indicate a sex-specific effect of EPHX2 in the manifestation of AN. Finally, high levels of EPHX2 expression were noted in the subcallosal gyrus, which has been implicated in depression and is functionally connected to the thalamus and limbic system.…”

Section: Resultsmentioning

confidence: 99%

Evidence for the role of EP HX2 gene variants in anorexia nervosa

et al. 2013

View full text Add to dashboard Cite

Anorexia nervosa (AN) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely rare and common genetic and environmental determinants. To identify genetic variants associated with AN, we pursued a series of sequencing and genotyping studies focusing on the coding regions and upstream sequence of 152 candidate genes in a total of 1205 AN cases and 1948 controls. We identified individual variant associations in the Estrogen Receptor-ß (ESR2) gene, as well as a set of rare and common variants in the Epoxide Hydrolase 2 (EPHX2) gene, in an initial sequencing study of 261 early-onset severe AN cases and 73 controls (p=0.0004). The association of EPHX2 variants was further delineated in: 1. a pooling-based replication study involving an additional 500 AN patients and 500 controls (replication set p=0.00000016); 2. Single locus studies in a cohort of 386 previously genotyped broadly-defined AN cases and 295 female population controls from the Bogalusa Heart Study (BHS) and a cohort of 58 individuals with self-reported eating disturbances and 851 controls (combined smallest single locus p<0.01). Since EPHX2 is known to influence cholesterol metabolism, and AN is often associated with elevated cholesterol levels, we also investigated the association of EPHX2 variants and longitudinal body mass index (BMI) and cholesterol in BHS females and males (N = 229) and found evidence for a modifying effect of a subset of variants on the relationship between cholesterol and BMI (p<0.01). These findings suggest a novel association of gene variants within EPHX2 to susceptibility to AN, and provide a foundation for future study of this important yet poorly understood condition.

show abstract

“…Cognitive distraction (attentional deployment) is achieved by focussing on food, eating, weight, shape, exercise and through the use of excessive exercise and purging behaviours. As the disorder progresses, the physiological impact of starvation numbs experience (Miller, Erickson, Branom, & Steiner, 2003a;Miller, Redlich, & Steiner, 2003b;Serpell, Teasdale, Troop, & Treasure, 2004) and starvation and emaciation enable a maladaptive expression of distress (Serpell, Neiderman, Haworth, Emmanueli, & Lask, 2003;Serpell, Treasure, Teasdale, & Sullivan, 1999Serpell et al, 2004).…”

Section: Emotion Generation Regulation and Anorexia Nervosamentioning

confidence: 99%