Habitual higher order aberrations affect Landolt but not Vernier acuity

Abstract

To assess whether the eye's optical imperfections are relevant for hyperacute vision, we measured ocular wave aberrations, visual hyperacuity, and acuity thresholds in 31 eyes of young adults. Although there was a significant positive correlation between the subjects' performance in Vernier- and Landolt-optotype acuity tasks, we found clear differences in how far both acuity measures correlate with the eyes' optics. Landolt acuity thresholds were significantly better in eyes with low higher order aberrations and high visual Strehl ratios ( r 2 = 0.22, p = 0.009), and significantly positively correlated with axial length ( r 2 = 0.15, p = 0.03). A retinal image quality metric, calculated as two-dimensional correlation between perfect and actual retinal image, was also correlated with Landolt acuity thresholds ( r 2 = 0.27, p = 0.003). No such correlations were found with Vernier acuity performance ( r 2 < 0.03, p > 0.3). Based on these results, hyperacuity thresholds are, contrary to resolution acuity, not affected by higher order aberrations of the eye.

Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision

“…In the subjective validation experiment, participants made an average error of 0.30 arcmin, corresponding to twice the objectively determined precision, and smaller than the expected Nyquist limit of 0.43 arcmin for a foveal cone density of 200,000 cells/mm 2 [36], but slightly higher than the typically found average Vernier acuity of 0.19 arcmin [37] and 0.25 arcmin [38]. Because we did not observe any systematic displacements across the three participants, we conclude that the subjective validation confirmed the current calibration process.…”

Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision

“…In the subjective validation experiment, participants made an average error of 0.30 arcmin, corresponding to twice the objectively determined precision, and smaller than the expected Nyquist limit of 0.43 arcmin for a foveal cone density of 200,000 cells/mm2 [36], but slightly higher than the typically found average Vernier acuity of 0.19 arcmin [37] and 0.25 arcmin [38]. Because we did not observe any systematic displacements across the three participants, we conclude that the subjective validation confirmed the current calibration process.…”

Retinal factors of visual sensitivity in the human fovea

“…High signal-to-noise ratio images were then generated by strip-wise image registration and averaging of individual frames of those videos, while manually excluding single frames with failed registration. In these normalized images, one human grader marked the location of each cone, assisted by convolutional neural network custom software (Cunefare et al, 2017; Reiniger et al, 2019). Matlab’s Voronoi function ( voronoiDiagram , Mathworks, Inc., Natick, MA, USA) was used to compute each cone’s area.…”

“…CC-BY-NC 4.0 International license made available under a (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is The copyright holder for this preprint this version posted March 16, 2021. ; https://doi.org/10.1101/2021.03.15.435507 doi: bioRxiv preprint cone, assisted by convolutional neural network custom software (Cunefare et al, 2017;Reiniger et al, 2019). Matlab's Voronoi function (voronoiDiagram, Mathworks, Inc., Natick, MA, USA) was used to compute each cone's area.…”