Haart induces the expression of HLA-G on peripheral monocytes in HIV-1 infected individuals

Blood soluble human leukocyte antigen G levels are associated with human immunodeficiency virus type 1 infection in Beninese commercial sex workers

“…Most HIV-1-infected individuals analyzed in the latter study were on antiretroviral therapy, whereas all of our study participants were naive to treatment. Antiretroviral therapy can induce surface expression of HLA-G on blood peripheral monocytes from HIV-1-infected patients [17,18]. Hence, the relatively high blood levels of HLA-G observed in the French subjects could be caused by antiretroviral therapy and not HIV-1 infection per se.…”

Modulation of HLA-G and HLA-E Expression in Human Neuronal Cells After Rabies Virus or Herpes Virus Simplex Type 1 Infections

“…One such molecule, the Ligand of Fas, FasL, has been shown to be involved in the killing of migratory T cells into the nervous system (NS) in rabies virus (RABV) infection [2,3]. HLA-G, a non classical MHC molecule which expression in cells is up regulated following infection with human cytomegalovirus (HCMV), human immunodeficiency virus (HIV-1) and RABV could also contribute by a similar mechanism to the immunoevasion of these viruses [4][5][6][7][8]. In addition, HIV-1 and HCMV up regulate the expression of another non classical MHC class I molecule,…”

Modulation of HLA-G Expression in Human Neural Cells after Neurotropic Viral Infections

“…However, HLA-G expression in cells is also upregulated following infection with human CMV and human immunodeficiency virus type 1 (5,34,49,50). HLA-G, which was originally thought to be present exclusively in the human placenta (7,9), has also been detected in brain and neural cells (35,70).…”