This paper presents a method for designing an active roll control system, combined with integrated chassis control for hybrid four-wheel-drive vehicles. The active roll control system adopts an active anti-roll bar as an actuator and is designed by model matching control with a roll estimator. To maintain the manoeuvrability of hybrid four-wheel-drive vehicles with an active roll control system, integrated chassis control is adopted. The hybrid four-wheel-drive vehicle consists of a front internal-combustion engine and independent motor-driven rear wheels and is equipped with electronic stability control, active front steering and four-wheel drive. Direct yaw moment control is used to generate a control yaw moment. Weighted pseudo-inverse-based control allocation and simulation-based optimization are proposed to distribute the control yaw moment. Simulations on the vehicle simulation software CarSim® show that the proposed active roll control system with integrated chassis control is effective for controlling the roll motion and the yaw motion of a hybrid four-wheel-drive vehicle.