H3K9me2 genome-wide distribution in the holocentric insect Spodoptera frugiperda (Lepidoptera: Noctuidae)

Repeat-based holocentromeres influence genome architecture and karyotype evolution

“…Repeat-based holocentromeres in beak-sedges comprise small islands (20-25 kb) of centromeric Tyba repeats, in which high mCpG, low H3K9me2, and depletion of H3K4me3 distinguish them from other holocentric genomes with and without repeatbased holocentromeres (Cortes-Silva et al, 2020;Despot-Slade et al, 2021;Nhim et al, 2022;Steiner and Henikoff, 2014). The association levels of H3K9me2 and mCHG at the core (low) and flanking (high) centromere units in R. pubera are strikingly similar to the recently reported A. thaliana centromeres (Naish et al, 2021).…”