“…TUG1, initially recognized as a transcript increased by taurine treatment in retinal cells, has been implicated in diverse cellular processes through its involvement in epigenetic regulation ( Duan et al, 2017 , Dieter et al, 2023a , Dieter et al, 2023b ). Although initially linked to retinal development and function, subsequent studies have revealed its broader implications in various biological contexts, including cancer, neurodegeneration, and, more recently, diabetes ( Bhat et al, 2022a , Bhat et al, 2022b , Bhat et al, 2022c , Esawy et al, 2022a , Esawy et al, 2022b ). The regulatory functions of TUG1 are mediated by its interactions with DNA, RNA, and proteins, suggesting its pivotal role in modulating gene expression networks.…”