H10: Long-Term Results Could Be Misleading Without an Updated Reading Key for Positron Emission Tomography

Vassilakopoulos, Theodoros P.; Liaskas, Athanasios; Pereyra, Patricio; Gallamini, Andrea

doi:10.1200/jco.23.02623

JCO

2024

DOI: 10.1200/jco.23.02623

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H10: Long-Term Results Could Be Misleading Without an Updated Reading Key for Positron Emission Tomography

Theodoros P. Vassilakopoulos,

Athanasios Liaskas,

Patricio Pereyra

et al.

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2024

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Toward a paradigm shift in prognostication and treatment of early‐stage Hodgkin lymphoma

Gallamini,

Filippi,

Camus

et al. 2024

Br J Haematol

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SummaryTwenty years after the conceptual revolution that occurred in the millennium turnaround upon the introduction of PET/CT in lymphoma staging, restaging, and prognostication, a number of new parameters for PET reading have been proposed: (1) the shift from a qualitative to a semi‐quantitative reading for PET reporting, (2) an international consensus on these novel interpretation keys, (3) a standardized and agreed procedure to measure the total metabolic tumour volume (TMTV), and (4) the proposition of new indexes to portray the tumour spread: (D‐Max and Total Lesion Surface –TLS). These proved to be very powerful prognosticators, able to revolutionize the traditional Ann Arbor four‐stage lymphoma staging. During the 17° Lugano meeting on lymphoma, one main question was asked to experts attending a closed workshop dedicated to new metrics for lymphoma diagnosis, staging, restaging, and prognostication: “Should the traditional 4‐stage anatomic staging system be simplified to a more clinically relevant 2‐stage system (e.g., limited vs. extensive disease)?” Early‐stage HL is an example of how these new metrics could fit with this proposal.

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Toward a paradigm shift in prognostication and treatment of early‐stage Hodgkin lymphoma

Gallamini,

Filippi,

Camus

et al. 2024

Br J Haematol

View full text Add to dashboard Cite

show abstract

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H10: Long-Term Results Could Be Misleading Without an Updated Reading Key for Positron Emission Tomography

Cited by 1 publication

References 7 publications

Toward a paradigm shift in prognostication and treatment of early‐stage Hodgkin lymphoma

Toward a paradigm shift in prognostication and treatment of early‐stage Hodgkin lymphoma

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