H<sub>1</sub>N<sub>1</sub>-associated Acute Retinitis

Rifkin, Lana M.; Schaal, Shlomit

doi:10.3109/09273948.2012.674611

Cited by 21 publications

(17 citation statements)

References 8 publications

(6 reference statements)

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“…80,201 This suggests that most, if not all, patients with herpetic retinitis have an underlying immunodeficiency that predisposes them to infection, even when they appear to be immunocompetent. 79,200 Although the pathogenesis in these individuals has yet to be established, further studies to determine the effect of virulence and host susceptibility in immunocompetent individuals in whom viral posterior uveitis is developed will be valuable in understanding the disease pathology.…”

Section: Viral Posterior Uveitismentioning

confidence: 99%

“…200 On examination, 59,200 there may be dense anterior chamber inflammation, vitritis, peripheral retinal necrosis, choroiditis, submacular hemorrhages, macular edema, neuroretinitis, vaso-occlusive retinal vasculitis, 35 frosted branch angiitis, 110 exudative retinal detachment, 233 and optic neuritis. 142,206 Other ocular conditions associated with H1N1 include uveal effusion syndrome 202 and orbital inflammatory syndrome.…”

Section: Viral Posterior Uveitismentioning

confidence: 99%

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Viral posterior uveitis

Lee

Agarwal

Mahendradas

et al. 2017

Survey of Ophthalmology

103

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The causes of posterior uveitis can be divided into infectious, autoimmune, or masquerade syndromes. Viral infections, a significant cause of sight-threatening ocular diseases in the posterior segment, include human herpesviruses, measles, rubella, and arboviruses such as dengue, West Nile, and chikungunya virus. Viral posterior uveitis may occur as an isolated ocular disease in congenital or acquired infections or as part of a systemic viral illness. Many viruses remain latent in the infected host with a risk of reactivation that depends on various factors, including virulence and host immunity, age, and comorbidities. Although some viral illnesses are self-limiting and have a good visual prognosis, others, such as cytomegalovirus retinitis or acute retinal necrosis, may result in serious complications and profound vision loss. Since some of these infections may respond well to antiviral therapy, it is important to work up all cases of posterior uveitis to rule out an infectious etiology. We review the clinical features, diagnostic tools, treatment regimens, and long-term outcomes for each of these viral posterior uveitides.

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Section: Viral Posterior Uveitismentioning

confidence: 99%

Section: Viral Posterior Uveitismentioning

confidence: 99%

Viral posterior uveitis

Lee

Agarwal

Mahendradas

et al. 2017

Survey of Ophthalmology

103

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“…In the context of the concept of 'original antigenic sin' it has been postulated that if there is an exposure of a child to an influenza virus for the first time there is development of strongest immunity in the later generations to come. As a result of this, there may be development of natural immunity to the A/H1N1 pdm pandemic virus that is circulating at the moment (Chowell et al 2011;Rifkin and Schaal 2012).…”

Section: Swine Influenzamentioning

confidence: 99%

Epidemiology of Influenza Viruses

Kapoor

Dhama

2014

Insight Into Influenza Viruses of Animals and Humans

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“…Patients infected with H1N1 may present with flu symptoms such as fever, cough and body aches [36,37]. Ocular involvement has been recently associated with H1N1 infection, as well as vaccination.…”

Section: H1n1 Uveitismentioning

confidence: 99%

“…It includes retinitis, choroiditis, submacular hemorrhages, macular edema, cotton wool spots, frosted branch angiitis, neuroretinitis, SRD, optic disc edema, and uveal effusion [36,37,38,39,40,41]. Ocular involvement is favorable in the majority of reported cases [36,37,38,39,40,41]. Frosted branch angiitis, macular edema, and uveal effusion may be treated with oral prednisone [38,40].…”

Section: H1n1 Uveitismentioning

confidence: 99%

New Infectious Etiologies for Posterior Uveitis

Khairallah

Kahloun²,

Yahia³

et al. 2012

Ophthalmic Res

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Emergent and resurgent arthropod vector-borne diseases are major causes of systemic morbidity and death and expanding worldwide. Among them, viral and bacterial agents including West Nile virus, Dengue fever, Chikungunya, Rift Valley fever, and rickettsioses have been recently associated with an array of ocular manifestations. These include anterior uveitis, retinitis, chorioretinitis, retinal vasculitis and optic nerve involvement. Proper clinical diagnosis of any of these infectious diseases is based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular involvement. The diagnosis is usually confirmed by the detection of a specific antibody in serum. Ocular involvement associated with emergent infections usually has a self-limited course, but it can result in persistent visual impairment. There is currently no proven specific treatment for arboviral diseases, and therapy is mostly supportive. Vaccination for humans against these viruses is still in the research phase. Doxycycline is the treatment of choice for rickettsial diseases. Prevention, including public measures to reduce the number of mosquitoes and personal protection, remains the mainstay for arthropod vector disease control. Influenza A (H1N1) virus was responsible for a pandemic human influenza in 2009, and was recently associated with various posterior segment changes.

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H₁N₁-associated Acute Retinitis

Cited by 21 publications

References 8 publications

Viral posterior uveitis

Viral posterior uveitis

Epidemiology of Influenza Viruses

New Infectious Etiologies for Posterior Uveitis

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H1N1-associated Acute Retinitis

Cited by 21 publications

References 8 publications

Viral posterior uveitis

Viral posterior uveitis

Epidemiology of Influenza Viruses

New Infectious Etiologies for Posterior Uveitis

Contact Info

Product

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H₁N₁-associated Acute Retinitis