H-scan analysis of thyroid lesions

Ge, Gary R.; Laimes, Rosa; Pinto, Joseph A.; Guerrero, Jorge; Chavez, Himelda; Salazar, Claudia; Lavarello, Roberto; Parker, Kevin J.

doi:10.1117/1.jmi.5.1.013505

Cited by 13 publications

(11 citation statements)

References 23 publications

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“…The red component is related to the low frequency information and represents the scatterer with a larger diameter, while the blue component is related to the high frequency information and represents the scatterer with smaller diameter [19][20][21][22][23]. The brightness of the red and blue components reflects the echo intensity of different scatterers.…”

Section: Discussionmentioning

confidence: 99%

“…Assume that a GH 4 (t) pulse is transmitted into a tissue; the pulse is backscattered, received, and convolved with a GH n matched filter [23]:…”

Section: Theorymentioning

confidence: 99%

“…H-scan can effectively display some information hidden in the conventional B-mode ultrasound image. Gary et al [23] used H-scan ultrasound imaging to analyze the nodules in different thyroid glands; the feasibility of H-scan to distinguish different size scatterers in tissues was demonstrated. Khairalseed et al [24] showed that H-scan ultrasound imaging is an effective tissue characterization technique and may have prognostic value in monitoring the response of early cancer to anticancer therapy.…”

Section: Introductionmentioning

confidence: 99%

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Classification of Benign and Malignant Breast Tumors Using H-Scan Ultrasound Imaging

Ouyang

Tsui

et al. 2019

Diagnostics

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Breast cancer is one of the most common cancers among women worldwide. Ultrasound imaging has been widely used in the detection and diagnosis of breast tumors. However, due to factors such as limited spatial resolution and speckle noise, classification of benign and malignant breast tumors using conventional B-mode ultrasound still remains a challenging task. H-scan is a new ultrasound technique that images the relative size of acoustic scatterers. However, the feasibility of H-scan ultrasound imaging in the classification of benign and malignant breast tumors has not been investigated. In this paper, we proposed a new method based on H-scan ultrasound imaging to classify benign and malignant breast tumors. Backscattered ultrasound radiofrequency signals of 100 breast tumors were used (48 benign and 52 malignant cases). H-scan ultrasound images were constructed with the radiofrequency signals by matched filtering using Gaussian-weighted Hermite polynomials. Experimental results showed that benign breast tumors had more red components, while malignant breast tumors had more blue components in H-scan ultrasound images. There were significant differences between the RGB channels of H-scan ultrasound images of benign and malignant breast tumors. We conclude H-scan ultrasound imaging can be used as a new method for classifying benign and malignant breast tumors.

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Section: Discussionmentioning

confidence: 99%

“…Assume that a GH 4 (t) pulse is transmitted into a tissue; the pulse is backscattered, received, and convolved with a GH n matched filter [23]:…”

Section: Theorymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Classification of Benign and Malignant Breast Tumors Using H-Scan Ultrasound Imaging

Ouyang

Tsui

et al. 2019

Diagnostics

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“…Recently, a new tissue characterization modality has emerged for the ultrasound classification of acoustic scatterers. [8][9][10][11][12][13] Termed H-scan ultrasound (where the H stands for hue or Hermite), this imaging approach links a special class of mathematical functions to the physics of ultrasound scattering and reflection from different tissue structures. In practice, digital filters are used to selectively analyze the spectral content of ultrasound backscattered echo signals and to colorize the display, providing visual or quantitative assessment of the major tissue scattering classes.…”

mentioning

confidence: 99%

“…Recently, a new tissue characterization modality has emerged for the ultrasound classification of acoustic scatterers . Termed H‐scan ultrasound (where the H stands for hue or Hermite), this imaging approach links a special class of mathematical functions to the physics of ultrasound scattering and reflection from different tissue structures.…”

mentioning

confidence: 99%

Monitoring Early Breast Cancer Response to Neoadjuvant Therapy Using H‐Scan Ultrasound Imaging: Preliminary Preclinical Results

Khairalseed

Javed

Gadhvi

et al. 2018

J of Ultrasound Medicine

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Objective— H-scan imaging is a new ultrasound technique used to visualize the relative size of acoustic scatterers. The purpose of this study was to evaluate the use of H-scan ultrasound imaging for monitoring early tumor response to neoadjuvant treatment using a preclinical breast cancer animal model. Methods— Real-time H-scan ultrasound imaging was implemented on a programmable ultrasound scanner (Vantage 256; Verasonics Inc., Kirkland, WA) equipped with an L11–4v transducer. Bioluminescence and H-scan ultrasound was used to image luciferase-positive breast cancer–bearing mice at baseline and at 24, 48, and 168 hours after administration of a single dose of neoadjuvant (paclitaxel) or sham treatment. Animals were euthanized at 48 or 168 hours, and tumors underwent histologic processing to identify cancer cell proliferation and apoptosis. Results— Baseline H-scan ultrasound images of control and therapy group tumors were comparable, but the latter exhibited significant changes over the 7-day study (P < .05). At termination, there was a marked difference between the H-scan ultrasound images of control and treated tumors (P < .05). Specifically, H-scan ultrasound images of treated tumors were more blue in hue than images obtained from control tumors. There was a significant linear correlation between the predominance of the blue hue found in the H-scan ultrasound images and intratumoral apoptotic activity (R2 > 0.40, P < .04). Conclusion— Preliminary preclinical results suggest that H-scan ultrasound imaging is a new and promising tissue characterization modality. H-scan ultrasound imaging may provide prognostic value when monitoring early tumor response to neoadjuvant treatment.

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Scatterer size estimation for ultrasound tissue characterization: A survey

Zhou,

Gao,

et al. 2024

Measurement

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H-scan analysis of thyroid lesions

Cited by 13 publications

References 23 publications

Classification of Benign and Malignant Breast Tumors Using H-Scan Ultrasound Imaging

Classification of Benign and Malignant Breast Tumors Using H-Scan Ultrasound Imaging

Monitoring Early Breast Cancer Response to Neoadjuvant Therapy Using H‐Scan Ultrasound Imaging: Preliminary Preclinical Results

Scatterer size estimation for ultrasound tissue characterization: A survey

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