The frequent presence of small echogenic foci within the inner myometrium in women who have had prior uterine instrumentation is reported. Bright foci were observed in 35 of 80 patients who had had prior dilatation and curettage or endocervical biopsy and in only 2 of 174 patients who gave no history of either procedure (P < 0.005). These foci tend to be small (3 to 6 mm), linear, usually nonshadowing, single or multiple, and located immediately adjacent to the endometrium anywhere along the length of the endometrial cavity; they can be seen many years after the D uring pelvic sonography, we have occasionally noted the presence of small, brightly echogenic foci within the inner layer (junctional zone) of the myometrium, close to the myometrialendometrial junction (Fig. 1). We were initially uncertain as to the cause of these foci but, through patient inquiries, we anecdotally found these foci likely to be related to prior uterine instrumentation. The present study was undertaken to confirm that the presence of these foci is statistically related to prior uterine instrumentation.
PATIENTS AND METHODSDuring a five month period, all women referred for nonobstetrical pelvic sonography were asked to comReceived September 17, 1990 from the Departments of Radiology and Clinical Investigation, Naval Hospital, San Diego, California. Revised manuscript accepted for publication February 8, 1991 .Address correspondence and reprint requests to LCDR Z. N. Balsara: c/o Clinical Investigation Department, Naval Hospital. San Diego, CA 92134-5000.The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the U.S. Government. procedure was performed. The histopathologic features of these foci are unconfirmed, but we suspect they represent calcification or fibrosis at sites of mechanical injury to myometrium. The presence of these foci serves as a marker of prior instrumentation and probably has no clinical significance. However, sonographers who are aware of their possible occurrence, can avoid mistaking them for leiomyoma calcifications or for air in the endometrium or myometrium in patients with suspected endometritis. plete a patient questionnaire relevant to their obstetrical and gynecologic medical history (Table 1). Of the 407 women referred for pelvic sonography during this time, questionnaires were completed and returned by 68% (277 patients). Twenty-three of these women had had hysterectomies and were excluded from analysis. The study group consisted of the remaining 254 patients.Transabdominal pelvic sonography with a full bladder technique was performed on all patients and many also underwent transvaginal sonography. All transab· dominal scans were obtained with a 3 MHz, 3.5 MHz, or 5 MHz transducer (Acuson, Mountain View, CA, and Advanced Technology Laboratories, Bothell, WA), and all transvaginal scans were obtained with a 5 MHz transducer. The presence or absence of small echogenic foci within the inner myome...