Gut permeability is associated with lower insulin sensitivity in youth with perinatally acquired HIV
Sahera Dirajlal-Fargo,
Wendy Yu,
Denise L. Jacobson
et al.
Abstract:The relationships between alterations in the intestinal barrier, and bacterial translocation with the development of metabolic complications in youth with perinatally-acquired HIV (YPHIV) have not been investigated.
The PHACS Adolescent Master Protocol enrolled YPHIV across 15 U.S. sites, including Puerto Rico, from 2007-2009. For this analysis, we included YPHIV with HIV viral load ≤1000 c/mL, with at least one measurement of homeostatic assessment of insulin resistance (HOMA-IR) or non-high densi… Show more
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