Gut microbiota metabolites: potential therapeutic targets for Alzheimer’s disease?
Shanshan Zhang,
Jing Lu,
Ziqi Jin
et al.
Abstract:BackgroundAlzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive decline in cognitive function, which significantly increases pain and social burden. However, few therapeutic interventions are effective in preventing or mitigating the progression of AD. An increasing number of recent studies support the hypothesis that the gut microbiome and its metabolites may be associated with upstream regulators of AD pathology.MethodsIn this review, we comprehensively explore the potential me… Show more
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