Gut microbiota is involved in the alleviation of loperamide‐induced constipation by honey supplementation in mice

Li, Yuyuan; Long, S. C.; Liu, Qiaochu; Ma, Hong; Li, Jianxin; Xin, Wei; Yuan, Jieli; Li, Ming; Hou, Binbin

doi:10.1002/fsn3.1736

Cited by 25 publications

(17 citation statements)

References 86 publications

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“…The prebiotic attribute of Jarrah honey on gut microbiota in mice resulted in a significant increase in faecal moisture level and relieving constipation due to the alteration of microbial ecology. The microbial diversity was largely enhanced on day 12 due to the application of honey, producing healthier gut ecosystems of the host [ 64 ]. Recently, melezitose and the carbohydrate profile of the Giant Willow Aphid ( Tuberolachnus salignus ) honeydew honey were identified [ 65 ].…”

Section: Prebiotic Properties Of Honeymentioning

confidence: 99%

A Sweeter Pill to Swallow: A Review of Honey Bees and Honey as a Source of Probiotic and Prebiotic Products

Mustar

Ibrahim

2022

Foods

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Honey bees and honey, have been the subject of study for decades due to their importance in improving health. At times, some of the probiotics may be transferred to the honey stored in the honeycomb. Consumers may benefit from consuming live-probiotics honey, which can aid in suppressing the reproduction of pathogens in their digestive system. Prebiotics, on the other hand, are mainly carbohydrates that promote the growth of native microflora probiotics in the digestive tract to maintain a healthy environment and improve the gut performance of the host. Therefore, this narrative review aims to present and analyze ten years’ worth of information on the probiotic and prebiotic potential of honey bees and honey since not many review articles were found discussing this topic. Results showed that not many studies have been performed on the probiotic and prebiotic aspects of honey bees and honey. If further research is conducted, isolated probiotics from the bee’s gut combined with honey’s prebiotic properties can be manipulated as potential sources of probiotics and prebiotics for human and animal benefits since they appear to be interrelated and function in symbiosis.

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Section: Prebiotic Properties Of Honeymentioning

confidence: 99%

A Sweeter Pill to Swallow: A Review of Honey Bees and Honey as a Source of Probiotic and Prebiotic Products

Mustar

Ibrahim

2022

Foods

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“…There is significant evidence of the prebiotic potential of honey from in vitro studies that assess the effect of honey on the growth of probiotic bacteria ( 100 – 107 ) and in probiotic food products, such as milk or yogurt, supplemented with honey ( 108 – 111 ). Numerous studies show that honey supports and promotes the growth of probiotic Bifidobacterium and Lactobacillus species, including B. longum , B. adolescentis , B. breve , B. bifidum , and B. infantis, Lactobacillus.…”

Section: The Prebiotic Potential Of Honeymentioning

confidence: 99%

“…As oligosaccharide composition can affect prebiotic activity, it is not surprising that different honeys can have different prebiotic properties ( 114 ). Honey can contain source-specific oligosaccharides ( 99 )for example, native New Zealand honeys showed high levels of isomaltose and melezitose ( 114 , 115 ), while raffinose was reported in Italian honey ( 116 ); and also different concentrations of commonly occurring oligosaccharides ( 107 ) influencing their prebiotic potential.…”

Section: The Prebiotic Potential Of Honeymentioning

confidence: 99%

“…Numerous in vivo studies using animal models show that honey acts as a prebiotic, specifically by promoting the populations of probiotic bacteria, including Bifidobacterium spp. and Lactobacillus spp., ( 104 , 106 , 107 , 119 ), and alleviating symptoms of constipation and ulcerative colitis ( 107 , 119 ). The prebiotic effect of honey has also been reported in shrimp, where honey promoted the growth of known probiotics Microbavterium spp., Lactobacillus spp., and Neptumonas spp.…”

Section: The Prebiotic Potential Of Honeymentioning

confidence: 99%

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The Potential of Honey as a Prebiotic Food to Re-engineer the Gut Microbiome Toward a Healthy State

Schell

Fernandes²,

Shanahan³

et al. 2022

Front. Nutr.

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Honey has a long history of use for the treatment of digestive ailments. Certain honey types have well-established bioactive properties including antibacterial and anti-inflammatory activities. In addition, honey contains non-digestible carbohydrates in the form of oligosaccharides, and there is increasing evidence from in vitro, animal, and pilot human studies that some kinds of honey have prebiotic activity. Prebiotics are foods or compounds, such as non-digestible carbohydrates, that are used to promote specific, favorable changes in the composition and function of the gut microbiota. The gut microbiota plays a critical role in human health and well-being, with disturbances to the balance of these organisms linked to gut inflammation and the development and progression of numerous conditions, such as colon cancer, irritable bowel syndrome, obesity, and mental health issues. Consequently, there is increasing interest in manipulating the gut microbiota to a more favorable balance as a way of improving health by dietary means. Current research suggests that certain kinds of honey can reduce the presence of infection-causing bacteria in the gut including Salmonella, Escherichia coli, and Clostridiodes difficile, while simultaneously stimulating the growth of potentially beneficial species, such as Lactobacillus and Bifidobacteria. In this paper, we review the current and growing evidence that shows the prebiotic potential of honey to promote healthy gut function, regulate the microbial communities in the gut, and reduce infection and inflammation. We outline gaps in knowledge and explore the potential of honey as a viable option to promote or re-engineer a healthy gut microbiome.

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“…Honey is reported to modify gut microbiome in constipated mice, 56 mice with ulcerative colitis, 57 and human intestinal microbe culture. 58 Experimental evidence shows that honey promotes the growth of health promoting species such as indigenous Bifidobacterium in cultures from human colon 58 while co-administration of bee honey with probiotic Bifidobacterium prevents the destruction of these bacteria by gastric secretions allowing a large number of cells to reach the intestine to produce their health-inducing activity.…”

Section: Figure 1 Schematic Illustration Of the Contribution Of Gut mentioning

confidence: 99%

Targeting Gut Microbiome and the Recovery of Muscle Loss Associated with Cancer (Cachexia): An Overview of the Possible Effect of Bee Products

Amira Mohammed Ali,

Esraa Mohammed Ali,

Mostafa Elsayed Ahmed

et al. 2021

MLU

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Current research emphasizes the contribution of gut microbiome to numerous health conditions including cancer and skeletomuscular disorders. Cachexia is a debilitating condition of progressive loss of body tissues. It occurs in up to 80% of patients with tumors, and it impairs their functioning and quality of life and increases morbidity and premature death. Several randomized trials indicate that interventions, which target gut microbiome can correct and revert tissue loss in aged people. However, less is known about the effect of such strategies in cachectic muscle loss. This report briefly sheds the light on the role of gut-muscle axis in cachexia and demonstrates few examples on interventions addressing gut microbiome and their effect on cachectic muscle. It also speculates the literature for the skeletal muscle-promoting activity of bee products, particularly bee honey and propolis (which are quite handy), within the context of cachexia. Implications for future studies are discussed.

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Gut microbiota is involved in the alleviation of loperamide‐induced constipation by honey supplementation in mice

Cited by 25 publications

References 86 publications

A Sweeter Pill to Swallow: A Review of Honey Bees and Honey as a Source of Probiotic and Prebiotic Products

A Sweeter Pill to Swallow: A Review of Honey Bees and Honey as a Source of Probiotic and Prebiotic Products

The Potential of Honey as a Prebiotic Food to Re-engineer the Gut Microbiome Toward a Healthy State

Targeting Gut Microbiome and the Recovery of Muscle Loss Associated with Cancer (Cachexia): An Overview of the Possible Effect of Bee Products

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