Gut microbiota-host lipid crosstalk in Alzheimer’s disease: implications for disease progression and therapeutics
Ya-Xi Luo,
Ling-Ling Yang,
Xiu-Qing Yao
Abstract:Trillions of intestinal bacteria in the human body undergo dynamic transformations in response to physiological and pathological changes. Alterations in their composition and metabolites collectively contribute to the progression of Alzheimer’s disease. The role of gut microbiota in Alzheimer’s disease is diverse and complex, evidence suggests lipid metabolism may be one of the potential pathways. However, the mechanisms that gut microbiota mediate lipid metabolism in Alzheimer’s disease pathology remain uncle… Show more
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