Gut Endocrine Cells in Birds: An Overview, with Particular Reference to the Chemistry of Gut Peptides and the Distribution, Ontogeny, Embryonic Origin and Differentiation of the Endocrine Cells

Rawdon, B.B.; Andrew, Ann

doi:10.1016/s0079-6336(99)80004-7

Cited by 38 publications

(39 citation statements)

References 145 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The distribution of CCK-immunoreactive cells is similar in birds and mammals (111). In ostrich, CCK is mainly produced in duodenum, whereas, in chicken, CCK production is concentrated at the transit from jejunum to ileum (61).…”

Section: Gut Cck-secreting Cellmentioning

confidence: 92%

See 1 more Smart Citation

How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to humans

Wang¹,

Cui²

2007

American Journal of Physiology-Regulatory, Integrative and Comp

View full text Add to dashboard Cite

Wang BJ, Cui ZJ. How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to humans. Am J Physiol Regul Integr Comp Physiol 292: R666-R678, 2007. First published October 19, 2006; doi:10.1152/ajpregu.00131.2006.-The field of cholecystokinin (CCK) stimulation of exocrine pancreatic secretion has experienced major changes in the recent past. This review attempts to summarize the present status of the field. CCK production in the intestinal I cells, the molecular forms of CCK produced and subsequently circulated in the blood, the presence or absence of CCK receptors on the isolated pancreatic acinar cells and the associated signaling for acinar cell secretion, and the actual circuits and sites of action for CCK regulation of exocrine pancreatic secretion in vivo are reviewed in different animal species with an emphasis on birds, rodents, and humans. Clear differences in the relative importance of neural and direct modes of CCK action on pancreatic acinar cells were identified. Rodents seem to be endowed with both modes of action, whereas in humans the neural mode may predominate. In birds, such as duck, the direct mode needs further assistance from pituitary adenylate cyclaseactivating peptide/VIP receptors. However, much further work needs to be directed to the neural mode to map out all sites of CCK action and details of the full circuits, and we foresee a major revival for this field of research in the near future. pancreatic acinar cells; vagal afferent nerves; plasma cholecystokinin concentration; species specificity IT IS GENERALLY ACCEPTED THAT cholecystokinin (CCK) as a gut hormone is an important endogenous secretagogue in exocrine pancreatic secretion. CCK also stimulates gallbladder contraction and enhances growth of the exocrine pancreas (63,115,138). CCK is produced and released by the intestinal mucosal I cells (78). This source of CCK may travel through the circulation to target tissues that include the exocrine pancreas and gallbladder (65,78). CCK peptides are also found in large quantities in neurons, but neuronal CCK contributes negligibly to CCK concentration in the circulation (118). This general picture has been changed drastically by the recent findings that CCK can also stimulate exocrine pancreatic secretion by the excitation of sensory nerves and vagovagal and enteropancreatic reflexes, and this may be the only pathway in humans (65, 105). In addition, major differences have been found in the traditional humoral pathway, depending on the animal species (35,149). Therefore, the purpose of this review is to present the current status of CCK regulation of exocrine pancreatic secretion with a particular emphasis on species specificity as shown in birds, rodents, and humans.

show abstract

Section: Gut Cck-secreting Cellmentioning

confidence: 92%

“…In ostrich, CCK is mainly produced in duodenum, whereas, in chicken, CCK production is concentrated at the transit from jejunum to ileum (61). Chicken CCK cell secretory granules are ϳ230 nm in diameter (111). In chicken, both dietary proteins and amino acids are potent stimulators of CCK release (37,150).…”

Section: Gut Cck-secreting Cellmentioning

confidence: 99%

How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to humans

Wang¹,

Cui²

2007

American Journal of Physiology-Regulatory, Integrative and Comp

View full text Add to dashboard Cite

show abstract

“…Gastrin immuno-reactive cells have been reported in the chicken proventriculus (Rawdon and Andrew, 1999;Martinez et al, 1993a). The numbers of these gastrin cells are increasing during late embryonic development (Aksoy and Cinar, 2009).…”

Section: Gastrinmentioning

confidence: 99%

Biology of the Gastrointestinal Tract in Poultry

Scanes

Pierzchała-Koziec

2014

Avian Biology Research

View full text Add to dashboard Cite

This review provides an overview of the anatomy and physiology of the gastro-intestinal tract (GIT) of poultry, particularly of the domesticated chicken. The structure and functioning of the major regions of the GIT are discussed bringing together recent studies with the older, often neglected, literature. Attention is focused on the GIT as an immune organ and on GIT fermentation/bacterial colonisation. In addition, the interactions of nutrition with GIT biology are discussed. The roles of neuropeptides and hormones on the development and functioning of the GIT are extensively reviewed.

show abstract

“…The secreted regulatory peptides control functions of the gastrointestinal tract that include motility, digestion and secretion [26]. The gastrin secreted by endocrine cells may stimulate both acid and pepsin secretion, while not influencing pancreatic secretion or gall bladder contraction [8,9,12].…”

Section: Introductionmentioning

confidence: 99%

Distribution and ontogeny of gastrin- and serotonin-immunoreactive cells in the proventriculus of developing chick, Gallus gallus domestica

Aksoy¹,

Çınar

2009

J Vet Sci

View full text Add to dashboard Cite

The ontogeny and distribution of gastrin- and serotonin-immunoreactive (IR) cell in the proventriculus of chicks (Gallus gallus domestica, n = 60) in different growth periods was examined immunohistochemically using antisera specific to gastrin and serotonin. Gastrin and serotonin-IR cells were detected in chick proventriculus. Gastrin-IR cells were first evident after 12 days of incubation in lamina epithelialis and compound glands, while serotonin-IR cells were observed only in compound glands at that same time. Gastrin-IR and serotonin-IR cells increased in frequency on incubation day 14 and 16, respectively. Towards the end of incubation, gastrin- and serotonin-IR cell numbers decreased. In adult chicken, both IR cells were present but not lower numbers. The observations demonstrate the presence of gastrin- and serotonin-IR cells in the proventriculus of developing chicks in temporally changing frequencies.

show abstract

Gut Endocrine Cells in Birds: An Overview, with Particular Reference to the Chemistry of Gut Peptides and the Distribution, Ontogeny, Embryonic Origin and Differentiation of the Endocrine Cells

Cited by 38 publications

References 145 publications

How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to humans

How does cholecystokinin stimulate exocrine pancreatic secretion? From birds, rodents, to humans

Biology of the Gastrointestinal Tract in Poultry

Distribution and ontogeny of gastrin- and serotonin-immunoreactive cells in the proventriculus of developing chick, Gallus gallus domestica

Contact Info

Product

Resources

About