Guinea Pigs

Pignon, Charly; Mayer, Jörg

doi:10.1016/b978-0-323-48435-0.00021-6

Cited by 12 publications

(14 citation statements)

References 57 publications

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“…Osteoarthritis may also occur secondary to dietary and husbandry factors in pet guinea pigs such as obesity, ulcerative pododermatitis, vitamin C deficiency or excess, inadequate exercise, improper substrate or joint trauma (Pignon and Mayer, 2021). Ovariectomy has also been shown to influence the development of osteoarthritis in female guinea pigs, with neutered animals more likely to develop this disease (Yuan et al, 2017).…”

Section: What Causes Osteoarthritis?mentioning

confidence: 99%

“…The mainstay of treatment is provision of appropriate analgesia long term, however physiotherapy, soft bedding and weight reduction in obese animals should also be recommended (Pignon and Mayer, 2021), (Table 1). Product recommendation can be difficult due to a wide variety of therapies being available, often with little data existing regarding their pharmacokinetics and efficacy, and dosing is often extrapolated from other species (Lennox, 2010).…”

Section: Treatment Options In Pet Guinea Pigsmentioning

confidence: 99%

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Osteoarthritis in pet guinea pigs: an update on diagnosis, treatment and management

Keeble

2021

Companion Animal

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This article reviews the current literature on osteoarthritis in pet and laboratory guinea pigs. The associated clinical signs, diagnosis and treatment of osteoarthritis in pet guinea pigs will be discussed, with options for analgesia detailed. This condition is thought to be common in pet guinea pigs, even from an early age in some genetic lines, although osteoarthritis often goes undiagnosed in this species until advanced disease is present, posing a major welfare concern. Increasing awareness of this condition in veterinary practitioners should aid early diagnosis in pets and help improve their quality of life. Prevention may be possible using oral protective nutritional supplements to slow down the progression of this disease at an early stage. Lifestyle changes are also discussed for the management of this condition in pet guinea pigs.

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Section: What Causes Osteoarthritis?mentioning

confidence: 99%

Section: Treatment Options In Pet Guinea Pigsmentioning

confidence: 99%

Osteoarthritis in pet guinea pigs: an update on diagnosis, treatment and management

Keeble

2021

Companion Animal

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“…Vitamin C deficiency can cause scurvy in guinea pigs which is indicated by coarse hair, limp, anorexia, slow wound healing, and joint swelling. Vitamin D deficiency causes fibrous osteodystrophy characterized by weight loss, hypersaliva, lethargy, and difficulty moving [5]. Deficiency of essential fatty acids can cause sores around the neck and ears, hair loss on the ventral surface, dermatitis, and stunted growth.…”

Section: Introductionmentioning

confidence: 99%

Hematology Profile of Female Guinea Pig (Cavia porcellus (Linnaeus, 1758)) with Diet Variations

Rahmani,

Rachid,

Fitria

2022

Advances in Biological Sciences Research

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Guinea pigs (Cavia porcellus (Linnaeus, 1758)) is a rodent other than rats and mice that are commonly used in biomedical research because of its physiological similarity to humans. To meet the requirement as a standard laboratory animal, the care management of GP needs to be controlled, one of which is by diet. The standard diet for GP is still limited in Indonesia, therefore GP is fed with a rabbit diet. According to references, inappropriate diet affects hematology profile. This research will be carried out to compare hematology profiles in GP fed with standard and nonstandard diets. Nine female GP were assigned into three groups, given a variety of diets based on the research design: Group BV (NS-NS-S), BVL (NS-S-S), and BL (S-S-S). The research lasted for 84 days, and blood was collected every 28 days. Hematology data profiled using fully automatic hematology analyzer Sysmex XP-100 with the following parameters:

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“…Guinea pig (Cavia porcellus) is traditionally used as a food animal [1] and the animal model in biomedical research [2]. In the last years, guinea pigs are also kept as house pets, a worldwide phenomenon [3,4]. Guinea pigs are the 6th most common treated animal species in veterinary practice in the United Kingdom [5].…”

Section: Introductionmentioning

confidence: 99%

“…Despite their popularity as pets and laboratory animals, there is still a lack of information about their morphology [6]. Although rodents are traditionally considered least variable mammals with a fixed number of seven cervical (C) and a total of 19 thoracolumbar vertebrae [7], varying number of thoracic (T), lumbar (L), sacral (S), and caudal (Cd) part of the vertebral column was previously published and summarised as following vertebral formula C7/T12-14/L6/S2-S4/Cd4-7 [4,[8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Vertebral Formulae and Congenital Vertebral Anomalies in Guinea Pigs: A Retrospective Radiographic Study

Proks

Johansen

Nývltová

et al. 2021

Animals

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The objectives of this retrospective study of 240 guinea pigs (148 females and 92 males) were to determine the prevalence of different vertebral formulae and the type and anatomical localization of congenital vertebral anomalies (CVA). Radiographs of the cervical (C), thoracic (Th), lumbar (L), sacral (S), and caudal (Cd) part of the vertebral column were reviewed. Morphology and number of vertebrae in each segment of the vertebral column and type and localization of CVA were recorded. In 210/240 guinea pigs (87.50%) with normal vertebral morphology, nine vertebral formulae were found with constant number of C but variable number of Th, L, and S vertebrae: C7/Th13/L6/S4/Cd5-7 (75%), C7/Th13/L6/S3/Cd6-7 (4.17%), C7/Th13/L5/S4/Cd6-7 (2.50%), C7/Th13/L6/S5/Cd5-6 (1.67%), C7/Th12/L6/S4/Cd6 (1.25%), C7/Th13/L7/S4/Cd6 (1.25%), C7/Th13/L7/S3/Cd6-7 (0.83%), C7/Th12/L7/S4/Cd5 (0.42%), C7/Th13/L5/S5/Cd7 (0.42%). CVA were found in 30/240 (12.5%) of guinea pigs, mostly as a transitional vertebra (28/30), which represents 100% of single CVA localised in cervicothoracic (n = 1), thoracolumbar (n = 22) and lumbosacral segments (n = 5). Five morphological variants of thoracolumbar transitional vertebrae (TTV) were identified. Two (2/30) guinea pigs had a combination of CVA: cervical block vertebra and TTV (n = 1) and TTV and lumbosacral transitional vertebra (LTV) (n = 1). These findings suggest that guinea pigs’ vertebral column displays more morphological variants with occasional CVA predominantly transitional vertebrae.

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Guinea Pigs

Cited by 12 publications

References 57 publications

Osteoarthritis in pet guinea pigs: an update on diagnosis, treatment and management

Osteoarthritis in pet guinea pigs: an update on diagnosis, treatment and management

Hematology Profile of Female Guinea Pig (Cavia porcellus (Linnaeus, 1758)) with Diet Variations

Vertebral Formulae and Congenital Vertebral Anomalies in Guinea Pigs: A Retrospective Radiographic Study

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