Guillain-Barre Syndrome After Minimally Invasive Transforaminal Interbody Fusion: A Case Report

Abode-Iyamah, Kingsley; Bohnen, Angela M.

doi:10.7759/cureus.6222

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…After an electromyogram, she was diagnosed with GBS and placed on IVIG. Abode-Iyamah et al [ 12 ] present a case of GBS after lumbar spine surgery. Postoperatively, their patient’s symptoms of paraesthesia, pain, and weakness relieved markedly.…”

Section: Discussionmentioning

confidence: 99%

Severe lumbar spinal stenosis combined with Guillain-Barré syndrome: A case report

Xu¹,

Wu²,

Yu³

et al. 2021

WJCC

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BACKGROUND Guillain-Barré syndrome (GBS) is a rare disorder that typically presents with ascending weakness, pain, paraesthesias, and numbness, which mimic the findings in lumbar spinal stenosis. Here, we report a case of severe lumbar spinal stenosis combined with GBS. CASE SUMMARY A 70-year-old man with a history of lumbar spinal stenosis presented to our emergency department with severe lower back pain and lower extremity numbness. Magnetic resonance imaging confirmed the diagnosis of severe lumbar spinal stenosis. However, his symptoms did not improve postoperatively and he developed dysphagia and upper extremity numbness. An electromyogram was performed. Based on his symptoms, physical examination, and electromyogram, he was diagnosed with GBS. After 5 d of intravenous immunoglobulin (0.4 g/kg/d for 5 d) therapy, he gained 4/5 of strength in his upper and lower extremities and denied paraesthesias. He had regained 5/5 of strength in his extremities when he was discharged and had no symptoms during follow-up. CONCLUSION GBS should be considered in the differential diagnosis of spinal disorder, even though magnetic resonance imaging shows severe lumbar spinal stenosis. This case highlights the importance of a careful diagnosis when a patient has a history of a disease and comes to the hospital with the same or similar symptoms.

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Section: Discussionmentioning

confidence: 99%

Severe lumbar spinal stenosis combined with Guillain-Barré syndrome: A case report

Xu¹,

Wu²,

Yu³

et al. 2021

WJCC

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Trauma-Related Guillain–Barré Syndrome: Systematic Review of an Emerging Concept

et al. 2020

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Guillain-Barré syndrome (GBS) is mainly associated with preceding exposure to an infectious agent, although the precise pathogenic mechanisms and causes remain unknown. Increasing evidence indicates an association between trauma-related factors and GBS. Here, we performed a systematic review, summarized the current scientific literature related to the onset of GBS associated with trauma, and explored the possible pathogenesis. A literature search of various electronic databases was performed up to May 2020 to identify studies reporting diverse trauma-related triggers of GBS. Data were extracted, summarized descriptively, and evaluated with respect to possible mechanisms. In total, 100 publications, including 136 cases and 6 case series involving GBS triggered by injury, surgery, intracranial hemorrhage, and heatstroke, met our eligibility criteria. The median age of the patients was 53 [interquartile range (IQR) 45-63] years, and 72.1% of the patients were male. The median number of days between the trigger to onset of GBS symptoms was 9 (IQR 6.5-13). Overall, 121 patients (89.0%) developed post-injury/surgical GBS, whereas 13 (9.6%) and 2 (1.5%) patients had preexisting spontaneous intracranial hemorrhage and heatstroke, respectively. The main locations of injury or surgeries preceding GBS were the spine and brain. Based on available evidence, we highlight possible mechanisms of GBS induced by these triggers. Moreover, we propose the concept of "trauma-related GBS" as a new research direction, which may help uncover more pathogenic mechanisms than previously considered for typical GBS triggered by infection or vaccination.

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Guillain-Barre Syndrome After Minimally Invasive Transforaminal Interbody Fusion: A Case Report

Cited by 2 publications

References 17 publications

Severe lumbar spinal stenosis combined with Guillain-Barré syndrome: A case report

Severe lumbar spinal stenosis combined with Guillain-Barré syndrome: A case report

Trauma-Related Guillain–Barré Syndrome: Systematic Review of an Emerging Concept

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