Guillain–Barré syndrome after Chikungunya infection: A case in Colombia

Villamil-Gómez, Wilmer E.; Silvera, Luz Alba; Páez-Castellanos, Jorge; Rodríguez-Morales, Alfonso J.

doi:10.1016/j.eimc.2015.05.012

Cited by 29 publications

(25 citation statements)

References 9 publications

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“…Tropical infections like Trypanosoma cruzi [36], CHIKV [14], and Dengue virus [41] were also associated with GBS cases in Colombia.…”

Section: Discussionmentioning

confidence: 99%

“…1). Table 1 summarizes the main characteristics of all studies [14,16,25,[31][32][33][34][35][36][37][38][39][40][41][42][43].…”

Section: Search Resultsmentioning

confidence: 99%

“…Only one article described the cause of the gastrointestinal infection (i.e., Salmonella) [31]. Moreover, four patients were diagnosed with CHIKV, Chagas disease, or Dengue virus (n = 2) infection in the workup done during the course of GBS [14,36,41]. Suckling mouse brain (SMB) rabies vaccination preceded the onset of neurological symptoms in 17 patients included in two studies [16,40].…”

Section: Pathophysiology and Immunopathologymentioning

confidence: 99%

“…The most common pathogen associated with GBS is Campylobacter jejuni [4]. In addition, GBS cases have been reported following cytomegalovirus [7], Epstein-Barr virus [8], Mycoplasma pneumoniae [9], Haemophilus influenza [10], influenza virus [11], Hepatitis E [12], Dengue [13], Chikungunya (CHIKV) [14] and Zika virus (ZIKV) infections [15], among others. Moreover, vaccination campaigns against influenza A (H1N1) [4] and rabies prophylactic vaccination [16] were associated with a small risk of GBS.…”

Section: Introductionmentioning

confidence: 99%

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Guillain–Barré syndrome in Colombia: where do we stand now?

Mahecha

Ojeda²,

Vega³

et al. 2016

Immunol Res

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Guillain-Barré syndrome (GBS) is a rapid-onset muscle weakness disease caused by the immune-mediated damage of the peripheral nervous system. Since there is an increase incidence of GBS cases in Latin America, particularly in Colombia, and most of them are currently preceded by Zika virus (ZIKV) infection, we aimed to assess the available evidence of the disease in Colombia through a systematic literature review. Out of 51 screened abstracts, only 16 corresponded to articles that met inclusion criteria, of which 15 were case reports or case series. A total of 796 cases of GBS were reported in the included articles. The majority of patients were males (66.8 %) and younger than 50 years old (94 %). An infectious disease before the onset of GBS was registered in 31 % of patients, with gastrointestinal or respiratory symptoms being the most frequently observed. In those cases in which electrodiagnostic tests were performed, the most common subphenotype was acute inflammatory demyelinating polyneuropathy (17 %). Death was reported in 15 % of patients. Data regarding GBS in Colombia is scant and heterogeneous. Taking into account the burden of the disease and the recent rise of GBS cases associated with ZIKV, a careful patient evaluation and a systematic collection of data are warranted. A form to data gathering is proposed.

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“…Tropical infections like Trypanosoma cruzi [36], CHIKV [14], and Dengue virus [41] were also associated with GBS cases in Colombia.…”

Section: Discussionmentioning

confidence: 99%

“…1). Table 1 summarizes the main characteristics of all studies [14,16,25,[31][32][33][34][35][36][37][38][39][40][41][42][43].…”

Section: Search Resultsmentioning

confidence: 99%

Section: Pathophysiology and Immunopathologymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Guillain–Barré syndrome in Colombia: where do we stand now?

Mahecha

Ojeda²,

Vega³

et al. 2016

Immunol Res

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“…At the same time, we observed an epidemiological cluster of cases Guillain-Barré syndrome (GBS), an acute and probably autoimmune demyelinating polyradiculoneuropathy that appears after a triggering (viral or bacterial) infection in almost two thirds of cases. GBS had already been associated with several arboviral diseases including chikungunya virus (CHIKV) infections [2,3], but a cluster as we reported here had never been described.…”

mentioning

confidence: 82%

Increase in cases of Guillain-Barré syndrome during a Chikungunya outbreak, French Polynesia, 2014 to 2015

et al. 2015

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During the recent chikungunya fever outbreak in French Polynesia in October 2014 to March 2015, we observed an abnormally high number of patients with neurological deficit. Clinical presentation and complementary exams were suggestive of Guillain–Barré syndrome (GBS) for nine patients. All nine had a recent dengue-like syndrome and tested positive for chikungunya virus (CHIKV) in serology or RT-PCR. GBS incidence was increased four- to nine-fold during this period, suggesting a link to CHIKV infection.

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The neurological complications of chikungunya virus: A systematic review

Mehta

Gérardin

Brito

et al. 2018

Reviews in Medical Virology

169

186

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SummaryWe performed a systematic review on the neurological complications of chikungunya virus. Such complications are being reported increasingly, owing primarily to the scale of recent epidemics but also to a growing understanding of the virus' neurovirulence. We performed a thorough literature search using PubMed and Scopus databases, summating the data on all published reports of neurological disease associated with chikungunya virus. We appraised the data for each major condition in adults, children, and neonates, as well as evaluating the latest evidence on disease pathogenesis and management strategies. The review provides a comprehensive summary for clinicians, public health officials, and researchers tackling the challenges associated with this important emerging pathogen.

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Guillain–Barré syndrome after Chikungunya infection: A case in Colombia

Cited by 29 publications

References 9 publications

Guillain–Barré syndrome in Colombia: where do we stand now?

Guillain–Barré syndrome in Colombia: where do we stand now?

Increase in cases of Guillain-Barré syndrome during a Chikungunya outbreak, French Polynesia, 2014 to 2015

The neurological complications of chikungunya virus: A systematic review

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