Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma

Extramedullary plasmacytoma involving perirenal space accompanied by extramedullary hematopoiesis and amyloid deposition

“…The absence of anemia and Bence-Jones proteinuria, as well as normal serum protein electrophoresis and normal bone marrow pathology, corroborate the diagnosis. 2 We could fi nd no report of a case with extrarenal capsule infi ltration using major search engines. Extramedullary plasmacytoma situated outside the renal capsule along the contour of the kidney, as in the present case, is rare.…”

Freiburg Neuropathology Case Conference: A Patient with Chronic Nasal Obstruction

“…In the head and neck region, EMPs occur mainly as a solitary tumor and only approximately 10 % are multiple. The diagnosis is based on the following criteria: (1) no bone marrow involvement; (2) pathological tissue evidence of monoclonal plasma cells involving a single extramedullary site; (3) no positive CRAB criteria (C = Calcium (elevated), R = Renal failure, A = Anemia, B = Bone lesions); and (4) low serum or urinary levels of monoclonal immunoglobulin [15].…”

“…To detect recurrence and progression to multiple myeloma, which occurs in 10-30 % of cases, radiological follow-up and electrophoresis assessment are required. The overall 10-year survival rate is ~ 70 % [12,15].…”

Plasmocitoma: desafio diagnostico em paciente idosa com apresentação clínica atípica. relato de caso

“…[1][2][3] Caracteriza-se por uma proliferação de CP monoclonais neoplásicas, com nenhuma evidência radiológica de lesões ósseas, ausência de sinais e sintomas de mieloma múltiplo (MM), presentes nas manifestações CRAB (hipercalcemia, insuficiência renal, anemia e/ou lesões ósseas) e uma medula óssea com exame morfologicamente normal ou com menos de 10% de CP. 4,5 Devido à raridade dessa doença, há poucos estudos sobre ela e não há um consenso acerca de seu prognóstico e tratamento. 6 O PS pode ser subdividido em duas entidades: plasmocitoma solitário ósseo (PSO) e plasmocitoma solitário extramedular (PEM), dependendo da origem da lesão.…”