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Cited by 28 publications
(24 citation statements)
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“…This indicate that our patients need to critical monitoring and cost, also they are high risk for other infection which are transmit to them during medical care. Same result shows in the previous study [12].…”
Section: Blood Transfusionsupporting
confidence: 87%
“…This indicate that our patients need to critical monitoring and cost, also they are high risk for other infection which are transmit to them during medical care. Same result shows in the previous study [12].…”
Section: Blood Transfusionsupporting
confidence: 87%
“…The most commonly used methods are reverse dot blot analysis and primer-specific amplification, with a set of probes or primers complementary to the most common mutations in the population from which the affected individual originated. If targeted mutation analysis fails to detect the mutation, HBB sequence analysis can be used to detect mutations in HBB gene [16].…”
Section: Molecular Genetic Analysismentioning
confidence: 99%
“…The objectives of transfusion therapy is to correct anemia, suppress erythropoiesis and inhibit gastrointestinal iron absorption that occurs in untransfused patients as a result of increased, albeit ineffective, erythropoiesis. The decision to start transfusion therapy in patients with confirmed diagnosis of beta-thalassemia should be based on the presence of severe anemia with hemoglobin (Hb) levels < 7 g/dL and any following clinical criteria: Facial changes, poor growth, spontaneous fractures and clinically significant extramedullary hematopoiesis [16]. The recommended treatment for betathalassemia major involves regular red blood cell transfusions throughout life, usually administered every two to five weeks depending on the transfusion needs of each individual in order to maintain the pre-transfusion level of hemoglobin between 9 and 10.5 g/dL [3] or higher (11-12 g/dL) for patients with cardiac complications and keep post-transfusion hemoglobin levels below 15 g/dL.…”
Section: Transfusion Therapymentioning
confidence: 99%
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