Guidelines for the veterinary care of laboratory animals: Report of the FELASA/ECLAM/ESLAV Joint Working Group on Veterinary Care

Abstract

Veterinary professionals working in partnership with other competent persons are essential for a successful animal care and use programme. A veterinarian's primary responsibilities are defined by their own professional regulatory bodies, but in this area of work there are further opportunities for contribution, which will assist in safeguarding the health and welfare of animals used in research. These guidelines are aimed not only at veterinarians to explain their duties, and outline the opportunities to improve the health and welfare of animals under their care, but also at employers and regulators to help them meet their responsibilities. They describe the desirability for postgraduate education towards specialization in laboratory animal medicine and detail the many competencies necessary to fulfil the role of the laboratory animal veterinarian. They detail the need for veterinary expertise to promote good health and good welfare of animals used in biomedical research during husbandry as well as when under experimental procedures. Regulatory and ethical aspects are covered as are the involvement of the veterinarian in education and training of others working in the animal care and use programme. Managerial aspects, including occupational health and safety, are also areas where the veterinarian's input can assist in the successful implementation of the programme.

Pterodon pubescens benth: stability study of microencapsulated extract and isolated compounds monitored by antinociceptive assays

“…route was used for all experiments, based on previous report. 12 Studies were carried out in accordance with the current guidelines for veterinary care of laboratory animals 14 and were performed under the consent and surveillance of Unicamp's Institute of Biology Ethics Committee for Animal Research (1951-1).…”

Comparison of Standardized Dichloromethane with Aqueous Pterodon pubescens Benth. Fruit Extracts on Antinociceptive and Anti-Inflammatory Activity

“…Studies were carried out in accordance with current guidelines for the veterinary care of laboratory animals and were performed under the consent and surveillance of UNICAMP's Institute of Biology Ethics Committee for Animal Research (2367-1). 26 All drugs and extracts were diluted in 1% Tween 80 ® vehicle (Sigma-Aldrich, USA) in 0.9% saline solution (NaCl diluted in distilled water). The following substances were used: dexamethasone (Sigma-Aldrich, USA), pentobarbital, (Cristália, Brazil), acetic acid, carrageenan (Sigma-Aldrich, USA), complete Freund adjuvant (SigmaAldrich, USA), and formaldehyde (Chemco, Brazil).…”

The European Framework on Research Animal Welfare Regulations and Guidelines

“…54 The power of annexes to Directives is that they may be updated without having to amend the core of a Directive. Methods of killing animals are subject to active debate and ongoing research.…”