Central blood pressure responses to exercise may provide clinicians with a superior diagnostic and prognostic tool. However, in order to be of value in a clinical setting these assessments must be simple to conduct and reliable. Objective: Using oscillometric pulse wave analysis (PWA), determine the upper limit for between-day reliability of central systolic blood pressure ( that, at least in a young health cohort, oscillometric PWA can be used to reliably assess central blood pressure measurements during exercise, up to a moderate intensity. While further work is required to validate these findings in clinical cohorts, these measurements may provide clinicians with a practical option for obtaining important hemodynamic information beyond that provided by resting peripheral blood pressure.