“…Typically, several apparently normal structures adjacent to the primary lesion and the majority of clinically negative neck nodal regions were included in this larger PTV, which also included a 3-mm setup margin (i.e., the expansion from low-dose CTV to low-dose PTV). The drawing of nodal regions included in the low-dose PTV was strictly based on the available guidelines (19,20). In general, nodal levels from 2 to 5 and retropharyngeal nodal regions were always included in the low-dose PTV, whereas submandibular (level IB) regions were included only in cases with bulky involvement of level IIA.…”