Objective-To expand the benefits of the minimally invasive direct coronary artery bypass (MIDCAB) concept to patients with multivessel disease, a hybrid procedure combining surgical revascularisation of the left anterior descending artery with interventional procedures for additional coronary lesions has recently been introduced. Preliminary results in patients undergoing this hybrid procedure are presented. Design and patients-Since December 1996, 35 patients (29 male, 6 female, mean (SD) age 56.7 (17) years) underwent a hybrid revascularisation performed as a primary MIDCAB procedure for grafting of the left anterior descending artery with the left internal mammary artery, followed by staged angioplasty and stenting of additional coronary lesions. Results-After MIDCAB grafting the postoperative course was uneventful in all patients. Coronary reangiography after a median of seven days revealed patent and functioning left internal mammary artery grafts in all patients. Applying subsequent percutaneous transluminal coronary angioplasty and occasional stenting (n = 14), a total of 47 lesions were treated successfully. Procedure related complications did not occur. All patients remained free from angina and no stress ECG changes were recorded. Conclusions-The preliminary results of this hybrid approach to myocardial revascularisation suggest that this is a safe and eVective procedure for complete revascularisation in selected patients with multivessel disease. Elderly and reoperative patients with significant comorbidity may benefit especially from such hybrid procedures by avoiding cardiopulmonary bypass and mid sternotomy. (Heart 2000;83:58-63) Keywords: hybrid revascularisation; minimally invasive cardiac surgery; interventional treatment; multivessel revascularisation Revascularisation of multivessel coronary artery disease with the left internal mammary artery (LIMA) and additional vein grafts using cardiopulmonary bypass and cardioplegic arrest currently represents the standard technique in coronary surgery.1 2 Despite continuing improvements in equipment and surgical technique, deleterious eVects of cardiopulmonary bypass, such as systemic inflammatory reactions, postoperative organ dysfunction, and coagulatory disorders, still pose problems.
3-5Aiming for less invasive cardiac surgery, several groups have reported encouraging results of coronary artery bypass grafting without cardiopulmonary bypass through conventional sternotomy or through diVerent minimised incisions. [6][7][8] In two larger series, a left anterolateral minithoracotomy was used to harvest the LIMA with subsequent coronary artery grafting of anterior vessels on a beating heart without cardiopulmonary bypass.9 10 Because of limited access through this incision, this approach cannot be applied for multivessel revascularisation without additional incisions or use of cardiopulmonary bypass.To expand the benefits of minimally invasive direct coronary artery bypass (MIDCAB) approaches to patients with multivessel disease, a "hybrid" p...