Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients

Dupuis, L. Lee; Robinson, Paula D.; Boodhan, Sabrina; Holdsworth, Mark T.; Portwine, Carol; Gibson, Paul; Phillips, Bob; Maan, Cathy; Stefin, Nancy; Sung, Lillian

doi:10.1002/pbc.25063

Cited by 59 publications

(50 citation statements)

References 44 publications

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“…They may also be of interest to administrators, educators, and researchers who make decisions about resource availability, provide professional education, and frame research questions about CIV and the supportive care of pediatric oncology patients. This CPG is one of a series on the subject of the prevention and management of CINV in pediatric oncology patients . The first of this series, a CPG on the emetogenicity of chemotherapy in children, was an adaptation of a guideline aimed at adult oncology patients .…”

Section: Introductionmentioning

confidence: 99%

Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline

Sing

Robinson

Flank

et al. 2019

Pediatric Blood & Cancer

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This clinical practice guideline (CPG) provides clinicians with recommendations regarding chemotherapy emetogenicity classification in pediatric oncology patients. This information is critically important for the appropriate selection of antiemetic prophylaxis. Recommendations are based on a systematic review limited to pediatric patients and a framework for classification when antiemetic prophylaxis is provided. Findings of 87 publications informed the emetogenicity classification of 49 single‐agent and 13 combination‐agent regimens. Information required for the classification of many chemotherapies commonly administered to pediatric patients is lacking. In the absence of pediatric data, consultation of methodologically sound CPGs aimed at adult oncology patients may be appropriate.

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Section: Introductionmentioning

confidence: 99%

Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline

Sing

Robinson

Flank

et al. 2019

Pediatric Blood & Cancer

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“…The three previously published guidelines address chemotherapy emetogenicity, prevention of acute CINV, and management of anticipatory CINV in children with cancer. [2][3][4] Complete versions of all four guidelines may be viewed at http://www.pogo.ca/healthcare/practiceguidelines/. Our recommendations are based on the assumption that children are receiving CINV prophylaxis that is consistent with the previously published guidelines.…”

Section: Introductionmentioning

confidence: 66%

Guideline for the Treatment of Breakthrough and the Prevention of Refractory Chemotherapy‐Induced Nausea and Vomiting in Children With Cancer

Flank

Robinson

Holdsworth

et al. 2016

Pediatric Blood & Cancer

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This clinical practice guideline provides an approach to the treatment of breakthrough chemotherapy-induced nausea and vomiting (CINV) and the prevention of refractory CINV in children. It was developed by an international, interprofessional panel and is based on systematic literature reviews. Evidence-based interventions for the treatment of breakthrough and prophylaxis of refractory CINV are recommended. Gaps in the evidence used to support the recommendations made in this clinical practice guideline were identified. The contribution of these recommendations to breakthrough and refractory CINV control in children requires prospective evaluation. Pediatr

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“…To identify current guidelines on the topics of interest, we asked all authors to state all contemporary, high‐quality, evidence‐based childhood cancer supportive care guidelines with which they were acquainted. This yielded 4 guidelines, which addressed 2 of the prioritized topics: fever and neutropenia and chemotherapy‐induced nausea and vomiting . Within these guidelines, we identified strong recommendations.…”

Section: Methodsmentioning

confidence: 99%

Current variations in childhood cancer supportive care in the Netherlands

Loeffen

Mulder

Wetering

et al. 2015

Cancer

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BACKGROUND: Current treatment strategies in pediatric oncology are intensive and lead to high survival rates but also to treatmentrelated complications. Therefore, supportive care plays an increasingly important role. This study was designed to evaluate variations in supportive care practice in children with cancer in the Netherlands and adherence to selected existing international guidelines through an in-depth review of local guidelines and protocols at all 6 Dutch pediatric cancer centers. METHODS: Based on shared expert opinion, a questionnaire regarding current supportive care practice was compiled. For each center, the required information was extracted from local supportive care guidelines, and the list was sent to a pediatric oncologist of that center to verify its correspondence with local daily practice. Subsequently, it was determined whether clinical practice was concordant (same in 5 of 6 centers), partly concordant (highly overlapping in 5 of 6 centers), or discordant (same in < 5 of 6 centers). Local practices were compared with strong recommendations from high-quality, evidence-based guidelines. RESULTS: The questionnaire comprised 67 questions regarding supportive care practice. Concordance was observed for 11 of 67 practice items (16%), partial concordance was observed for 6 of 67 practice items (9%), and discordance was observed for 50 of 67 practice items (75%). Adherence to strong recommendations of 4 high-quality, evidence-based guidelines varied but was generally low. CONCLUSIONS: Large variations exist in pediatric oncology supportive care practice, and this could negatively influence care. Adherence to existing evidence-based guidelines and the development and implementation of new clinical practice guidelines have the potential of standardizing supportive care practice and thereby improving outcomes for children with cancer. Cancer 2016;122:642

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Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients

Cited by 59 publications

References 44 publications

Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline

Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline

Guideline for the Treatment of Breakthrough and the Prevention of Refractory Chemotherapy‐Induced Nausea and Vomiting in Children With Cancer

Current variations in childhood cancer supportive care in the Netherlands

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