Guided web-based treatment program for reducing cannabis use: a randomized controlled trial

Sinadinovic, Kristina; Johansson, Magnus; Johansson, Ann Sofie; Lundqvist, Thomas; Lindner, Philip; Hermansson, Ulric

doi:10.1186/s13722-020-00185-8

Cited by 18 publications

(51 citation statements)

References 33 publications

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“…Users of the therapist-led intervention had greater decrease in alcohol consumption at 3 months compared to the control, although other time by group effects were not significant (38). The trial targeting regular cannabis use (N = 303) compared a guided self-help intervention with a waitlist control (WLC) in a ratio of (1:1), showing no significant time by group effects on cannabis use at the 3-month followup, yet such effects were revealed in the subset of participants that had not sought other professional help during the trial (39). In both trials, all participants were asked to rate their attitudes toward internet interventions (see full description of measure below) before entering the program, of which n = 1,037 + 256 participants answered the form, implying a coverage rate of 89% and 84% in the alcohol and cannabis program, respectively.…”

Section: Methods Sample and Proceduresmentioning

confidence: 98%

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Impact of Users' Attitudes Toward Anonymous Internet Interventions for Cannabis vs. Alcohol Use: A Secondary Analysis of Data From Two Clinical Trials

et al. 2021

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Background: Numerous trials have demonstrated the efficacy of internet interventions targeting alcohol or cannabis use, yet a substantial proportion of users do not benefit from the format, warranting further research to identify moderators of treatment effects. Users' initial attitudes toward treatment is a potential moderator, yet no previous study has investigated users' attitudes in the context of internet interventions for addictive disorders.Method: In this secondary analysis on two internet-based trials targeting harmful alcohol use (n = 1,169) and regular cannabis use (n = 303), respectively, we compared user groups' attitudes at the item level; explored within-group heterogeneity by submitting attitude scores to a k-means cluster analysis; and investigated whether latent subgroups in each user group moderated the treatment effects. Outcome models were run using generalized linear models with 10,000 bias-corrected bootstraps accounting for subject-level clustering.Results: While substance groups and latent subgroups converged in enjoying the anonymity provided by the format, their interest toward treatment differed. Outcome analyses revealed a significant and negative time by subgroup effect on grams of cannabis consumed and screening test score (CAST), favoring the subgroup with positive treatment attitudes. There were not any significant effects of subgroup on alcohol consumption. Despite initial treatment reluctance, participants in the neutral subgroup decreased their cannabis use (gram) significantly when receiving the intervention vs. control.Conclusions: This first, exploratory study revealed key differences between substance groups' attitudes, but more importantly that within-group heterogeneity appear to affect cannabis outcomes. Assessing attitudes could be key in patient-treatment matching, yet more research is needed.

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Section: Methods Sample and Proceduresmentioning

confidence: 98%

“…This study is a secondary analysis of data from two randomized controlled trials of internet interventions for harmful alcohol use or dependence (38) and regular cannabis use (39), respectively. See each respective publication for details on participant recruitment, procedure, treatments and full outcomes reporting.…”

Section: Methods Sample and Proceduresmentioning

confidence: 99%

Impact of Users' Attitudes Toward Anonymous Internet Interventions for Cannabis vs. Alcohol Use: A Secondary Analysis of Data From Two Clinical Trials

et al. 2021

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“…Notably, while smartphone apps are promising, the review by Colbert et al [ 9 ] shows that current evidence for apps targeting unhealthy alcohol use is still limited compared with available evidence for internet-based interventions. Focusing on cannabis use among adults and adolescents, Sinadinovic et al [ 10 ] showed that a web-based treatment program with therapist guidance was not superior to a waiting list design, although subgroup analyses showed that the intervention may be beneficial for some.…”

Section: Special Issue Themesmentioning

confidence: 99%

Information technology and addiction science: promises and challenges

Bertholet

Cunningham

2021

Addict Sci Clin Pract

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Background Information technology can be used to advance addiction science and clinical practice. Main body This special issue, “Information technology (IT) interventions to advance treatment for opioid and other addictions” presents studies that expand our understanding of IT intervention efficacy, patients’ perspectives, and how IT can be used to improve substance use health care and research. This editorial introduces the topics addressed in the special issue and focuses on some of the challenges that the field is currently facing, such as attrition and treatment retention, transferability of intervention paradigms, and the challenge to keep pace with rapidly changing technologies. Conclusions Increasing treatment reach is particularly crucial in the addiction field. IT empowers researchers and clinicians to reach large portions of the population who might not otherwise access standard treatment modalities, because of geographical limitations, logistical constraints, stigma, or other reasons. The use of information technology may help reduce the substance use treatment gap and contribute to public health efforts to diminish the impact of substance use and other addictive behaviors on population health.

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“…An encouraging example is Lundqvist and Ericsson’s ‘Cannabis Cessation Program’ (CCP, Nordic abbreviation: HAP), developed in the 1990s, which has spread and is currently used in many Swedish municipalities [ 7 , 8 ]. The model has mainly been used as an individual-based intervention [ 9 ], but it has also been tested in a group format and in online formats [ 10 – 12 ].…”

Section: Introductionmentioning

confidence: 99%

Successful outcomes with low–threshold intervention for cannabis use disorders in Norway - an observational study

Vederhus

Rørendal²,

Skårdal³

et al. 2022

PLoS ONE

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Aims Cannabis is the most commonly used regulated drug by European youths. Yet, few cannabis-specific interventions have been examined in Europe. The Cannabis Cessation Program (CCP) was developed in Sweden in the 1990s and has been implemented in some Norwegian municipalities. The present study aimed to examine outcomes of this intervention in the Norwegian setting. Method The respondents (N = 102) were recruited in four community-based CCPs in Norway. We examined their changes in cannabis use, other substance use, mental distress, well-being, sense of coherence (SoC), and social networks, from baseline (T0) to post-treatment (T1) and up to a 3-month follow-up period (T2). Changes were evaluated with pair-wise t-tests. Result Seventy-six participants (75%) completed the 8-week program, according to plan. All participants reported a significant reduction in cannabis use at T1 (average reduction ~16 days per month) and at T2 (N = 59; ~13 days per month). Among those that completed the program, 67% was abstinent from cannabis at T1 and 37% was abstinent at T2. An intention-to-treat analysis showed that 50% (51/102) and 22% (22/102) were abstinent from cannabis use at T1 and T2, respectively. In parallel to abstinence, we observed a substantial reduction in mental distress and an increase in well-being and SoC. Respondents socialized with fewer friends with current substance use, but drug-free social networks were not expanded. Conclusion Our findings suggested that the CCP was a valuable, low-threshold manual-based intervention for cannabis use disorders. It showed considerable potential for reducing individuals’ cannabis use. Clinical trial registration Clinicaltrials.gov no. NCT04989205. Registered 12 July 2021, i.e., the study was retrospectively registered.

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Guided web-based treatment program for reducing cannabis use: a randomized controlled trial

Cited by 18 publications

References 33 publications

Impact of Users' Attitudes Toward Anonymous Internet Interventions for Cannabis vs. Alcohol Use: A Secondary Analysis of Data From Two Clinical Trials

Impact of Users' Attitudes Toward Anonymous Internet Interventions for Cannabis vs. Alcohol Use: A Secondary Analysis of Data From Two Clinical Trials

Information technology and addiction science: promises and challenges

Successful outcomes with low–threshold intervention for cannabis use disorders in Norway - an observational study

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