Guided Bone Regeneration in a Periodontally Compromised Individual with Autogenous Tooth Bone Graft: A Radiomics Analysis

Abstract

Background: Autogenous tooth bone graft material (AutoBT) has been advocated as a bone substitute when conducting alveolar ridge preservation. This study is aimed at using a radiomics approach in order to evaluate and testify whether AutoBT can stimulate bone growth during socket preservation in severe periodontal cases. Materials and Methods: For this study, 25 cases with severe periodontal diseases were selected. The patients’ AutoBTs were inserted into the extraction sockets and covered with Bio-Gide® collagen membranes. 3D CBCT scans and 2D X-rays were taken of the patients before surgery and after 6 months post-surgery. For the retrospective radiomics analysis, the maxillary and mandibular images were compared in different groups. Maxillary bone height was analyzed at the buccal, middle, and palatal crest sites, while the mandibular bone height was compared at the buccal, center, and lingual crest sites. Results: In the maxilla, the alveolar height was increased by −2.15 ± 2.90 mm at the buccal crest; −2.45 ± 2.36 mm at the center of the socket, and −1.62 ± 3.19 mm at the palatal crest, while the height of the buccal crest was increased by 0.19 ± 3.52 mm, and the height at the center of the socket was increased by −0.70 ± 2.71 mm in the mandible. The three-dimensional radiomics analysis demonstrated significant bone growth in the local alveolar height and high density. Conclusion: Based on clinical radiomics analysis, AutoBT could be used as an alternative bone material in socket preservation after tooth extraction in patients with severe periodontitis.

Regeneration of Rabbit Calvarial Defects with Combination of Stem Cells and Enamel Matrix Derivative: A Microcomputed Tomography and Histological Evaluation Comparing Two- and Three-Dimensional Cell Constructs

“…This promotion is crucial for the regeneration of these structures. Similarly, guided bone regeneration uses membranes to induce bone regeneration in areas suffering from bone loss due to periodontal disease [ 30 ]. The membrane creates an environment where bone cells can migrate, proliferate, and mature, helping to restore lost alveolar bone.…”

Photobiomodulation Therapy Improves Repair of Bone Defects Filled by Inorganic Bone Matrix and Fibrin Heterologous Biopolymer

“…For repair to occur effectively, it depends on a number of factors, such as care taken with the surgical environment, surgical margins, vascular proliferation, migration of undifferentiated cells, the presence of a fibrin network and, when possible, preserving the periosteum and endosteum [9][10][11]. When bone repair does not take place in the injured area, the lesion will be filled with fibrous connective tissue and the tissue will not recover its original functionality [1,12,13]. In cases where one of these factors cannot be preserved, biomaterials can be used to recompose the bone tissue [14][15][16][17].…”

Inter and intra‐operator reliability of Lekholm and Zarb classification and proposal of a novel radiomic data‐driven clustering for qualitative assessment of edentulous alveolar ridges

“…In head and neck area, radiomics has been mainly applied on CT and CBCT imaging for the automated diagnosis, segmentation, and classification of various conditions, including jaw cysts and tumors, cervical lymph node metastasis, salivary gland diseases, temporomandibular joint disorders, maxillary sinus issues, mandibular fractures, and facial deformities (Hung et al., 2022). Nevertheless, there has been a very limited utilization of radiomics potential in the field of oral implantology (Li et al., 2023; Troiano et al., 2023).…”