Guided bone generation in a rabbit mandible model after periosteal expansion with an osmotic tissue expander

Abstract

This study confirms that an osmotic soft tissue expander creates a surplus of periosteum and soft tissue, and that new bone can subsequently be generated under a titanium mesh with the use of an autologous bone graft or DBBM.

Pre‐augmentation soft tissue expansion: an overview

“…), and (ii) promising results after mucosal expansion have been described in previous animal experiments (Abrahamsson et al. , ).…”

“…), others did not observe any signs of bone loss (Uijlenbroek et al., ) or even documented new bone formation (Abrahamsson et al. , , ).…”

“…In contrast, Abrahamsson and co‐workers suggested that placing the expanders in a sub‐periosteal location induced slow expansion of the periosteum which resulted in new bone formation at the periphery of the expanders (Abrahamsson et al. , , ) without any signs of bone resorption underneath these devices. They assumed that the slow expansion of the periosteum activated osteogenic cells which enhanced bone formation.…”

“…The effect of soft tissue expansion on the outcomes of GBR with two different grafting materials was evaluated in an another animal study (Abrahamsson et al. ). In agreement with previous findings, soft tissue expanders were able to create a surplus of soft tissues including periosteum, which facilitated mucosal coverage of the bone graft without occurrence of soft tissue dehiscences.…”

Periosteal Distraction Osteogenesis: An Effective Method for Bone Regeneration

“…To overcome the manual operation problem, Abrahamsson et al [22, 42, 43] put a self-inflatable osmotic expander under the mandibular periosteum of rabbits and then placed a preformed scaffold that was filled with autogenous bone graft or bone substitute; finally the distraction device acquired newly formed bone after three months. Yamauchi et al [31, 32, 38] then designed a new type of self-activated memory alloy (SMA) (Figure 1(c)); it does not need distraction screws and thus solves the complications with the minimal invasion.…”