Guía de actuación ante Staphylococcus aureus resistente a meticilina (SARM) en centros gerontológicos, sociosanitarios y unidades de media-larga estancia

Alkiza, María E.; Arriola, Enrique; Basterretxea, Mikel; Díaz, Ibraín Piloto; Esparza, Macias; García-Arenzana, José María; Robertson, M.; Sáenz, Julián Ruiz; Wichmann, Miguel Ángel von

doi:10.1016/s0211-139x(04)74982-3

Cited by 9 publications

(5 citation statements)

References 7 publications

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“…According to microbiological sampling, both infections described in this study were related, and we can state that cross infection occurred in our center as it was detected within a period of less than one month [ 3 , 8 ]. One of the most important procedures implemented in our unit is hand hygiene at the start and end of the working day and before and after seeing every patient.…”

Section: Discussionmentioning

confidence: 99%

“…Despite the fact that MRSA is usually sensitive to topical antibiotics, such as mupirocin or fusidic acid, it is preferable not to use them in patients with chronic ulcers such as FPI, because the pathogen easily becomes resistant to them. [ 8 ]. Thus, in our guidelines for managing diabetic ulcers, local antibiotic therapy is not presented.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have revealed that DFIs are polymicrobial, including bacterial flora ( Staphylococcus aureus , Streptococcus epidermidis , Peptococcus, and Bacteroides fragilis ) [ 6 , 7 ]. Staphylococcus aureus is the most commonly isolated microorganism [ 6 , 7 , 8 , 9 ], but the extended spectrum beta-lactamases Klebsiella and Pseudomonas aeruginosa can also be detected in small concentrations, increasing the risk of limb amputation [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…The most important mechanism of the propagation of MRSA and the other microorganisms cited below is contact between people. The most common transfer is from one person to another by means of contaminated hands of healthcare/auxiliary personnel who do not wash them correctly between one patient and the next [ 8 ]. Transmission because of contamination of healthcare material and/or surfaces has also been reported and is known as healthcare-associated infection (HAI).…”

Section: Introductionmentioning

confidence: 99%

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Methicillin-Resistant Staphylococcus aureus Diabetic Foot Crossed Infection: A Case Report

et al. 2020

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This work presents a protocol to prevent the transmission of multidrug-resistant infections. We focus on the Diabetic Foot Unit Podiatry Clinic Area attached to the University of Seville in particular. The most common complication for patients with diabetes is leg ulcers. Together with neuropathy, vasculopathy, and immunological response disorder, these individuals have a high predisposition to developing infections. Staphylococcus aureus is a highly prevalent microorganism in humans which, at times, may act as a pathogen. Due mainly to indiscriminate abuse of antibiotics, the methicillin-resistant strain known by its initials as MRSA is the most extended nosocomial infection globally and is a severe community and hospital healthcare problem. This paper describes compliance with new general recommendations on cleaning, hygiene, and decontamination, in addition to implementation of this specific protocol, after detection of cross infection (healthcare-related infection) in the studied unit in two patients with MRSA-infected ulcers. After an in-depth bibliographical review, strict hand hygiene measures and use of non-sterile gloves were used when treating all patients with a diabetic foot. Finally, we reflect on the need to educate healthcare personnel to guarantee correct prescription of selected antibiotics. The role of the podiatrist in the multidisciplinary team is highlighted not only in terms of management and treatment of lesions in diabetic patients, but also as a healthcare agent for the detection and prevention of MRSA together with other multidrug-resistant infections.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Methicillin-Resistant Staphylococcus aureus Diabetic Foot Crossed Infection: A Case Report

et al. 2020

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“…This impact is related to the fact that there is an increasing level of antibiotic resistant bacteria and in this case, therapeutic options available are quite limited. Specifically, Staphylococcus aureus Methicillin Resistant (MRSA resistant to all available penicillin and almost all β -lactam antibiotics) is the leading cause of skin infections ( Alkiza et al, 2004 ; Doron and Gorbach, 2008 ; Ki and Rotstein, 2008 ; Stevens et al, 2014 ) in nosocomial infections as well as in community settings ( Vingsbo Lundberg and Frimodt-Møller, 2013 ; World Health Organization, 2020 ). The severity of the infection in the skin is classified according to the presence of impetigo (minor infection) and eczema, ulcers, as well as lacerations (secondary infection).…”

Section: Introductionmentioning

confidence: 99%

Formulation of a novel antibacterial topical treatment based on Magnetite-Buforin-II-silver nanobioconjugates

Muñoz

Jaramillo

Gantiva-Diaz

et al. 2022

Front. Bioeng. Biotechnol.

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Community acquired infections caused by Meticillin-resistant Staphylococcus aureus (MRSA) have become a growing concern due to its impact on the world public health. This microorganism is a commonly spreading pathogen associated predominantly with skin infections and connected to other more severe conditions (septic shock, and generalized infection). The lack of highly effective antibiotics and treatments to control skin infections with S. aureus has led to the search of novel therapies using alternative agents such as antimicrobial peptides (AMPs). In order to obtain a viable administration route to counteract superficial skin infections (impetigo, abscesses, furuncles, and cellulitis), a topical formulation based on Magnetite-Buforin-II-silver nanobioconjugates as active antibacterial agents was designed by their dispersion in O/W concentrated emulsions. The prepared topical characterization indicated that O/W emulsions were stable in time, the droplets size remained within the appropriate values (∼1 µm) and their rheological properties, such as pseudoplastic and shear-thinning behavior, remained unchanged for up to 3 months. Additionally, hemolysis and platelet aggregation tests were acceptable (i.e., 14.72 ± 2.62% and 8.06 ± 2.90%, respectively) in compliance with the ISO-10993 standard. Furthermore, the treatment reduced significantly (p < 0.0001) the growth of both clinical isolated MRSA and wild Type S. aureus strains as evidenced by the contact diffusion method. These results are important in the context of proposing new alternatives that allow manage effectively the threat posed by the antibiotic resistant bacterial strains, which jeopardize the lives of thousands of people every year.

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Volatile organic compound produced by bacteria: characterization and application

Herrera-Cabrera,

Delgado-Alvarado,

Salgado-Garciglia

et al. 2024

Bacterial Secondary Metabolites

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Guía de actuación ante Staphylococcus aureus resistente a meticilina (SARM) en centros gerontológicos, sociosanitarios y unidades de media-larga estancia

Cited by 9 publications

References 7 publications

Methicillin-Resistant Staphylococcus aureus Diabetic Foot Crossed Infection: A Case Report

Methicillin-Resistant Staphylococcus aureus Diabetic Foot Crossed Infection: A Case Report

Formulation of a novel antibacterial topical treatment based on Magnetite-Buforin-II-silver nanobioconjugates

Volatile organic compound produced by bacteria: characterization and application

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