Conventional arthroscopy is performed with a narrow tube, the arthroscope, attached to a camera and two cables - one for power and one for fiber-optic light. The cables can be cumbersome, routed across or around the patient, and risk bridging the sterile and nonsterile fields. ArthroFree®, a wireless surgical camera for arthroscopy, features wireless communication and battery power and was designed to eliminate cable-associated burdens. An iterative product development process established the usability of ArthroFree. Feedback on ArthroFree’s design was received from 88 participants (82 surgeons and 6 other medical professionals) on ergonomics, ease of use, image quality, and patient experience following design validation testing (pre-FDA clearance; 76 participants) or clinical evaluation (post-FDA clearance; 12 participants). Participants were trained on the use of ArthroFree and then used the device in a surgical procedure performed on a cadaver, simulated model, or patient. Their experience was evaluated in a 13-statement human factors survey scored using a 5-point Likert scale. ArthroFree scored well in all survey statements, scoring “good” or “excellent” (4.5 mean score), suggesting users’ needs were satisfied in 91.30% of participants. Additionally, one-on-one interviews with surgeons gathered qualitative feedback on their independent experience with the ArthroFree device, providing key support for its introduction to the operating room.