Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast

Abstract

18Septin proteins co-assemble into hetero-oligomers that polymerize into cytoskeletal filaments with 19 a variety of cellular functions. In Saccharomyces cerevisiae, where septins were first discovered, 20 five subunits comprise two species of septin hetero-octamers,