Guanfacine as a Facilitator of Recovery from Conversion Disorder in a Young Girl

Neuromodulation Using Computer-Altered Music to Treat a Ten-Year-Old Child Unresponsive to Standard Interventions for Functional Neurological Disorder

“…As was evident in MT’s case, patients with functional seizures often present in a high state of physiological arousal 85 . Given that alpha agonist medications, such as the guanfacine used with MT, often decrease sympathetic arousal, they may be helpful with FND symptoms 86,87 . Anticonvulsants are also often prescribed for patients with FND.…”

“…85 Given that alpha agonist medications, such as the guanfacine used with MT, often decrease sympathetic arousal, they may be helpful with FND symptoms. 86,87 Anticonvulsants are also often prescribed for patients with FND. Some studies have found that anticonvulsants can potentially reduce the frequency of episodes, but this finding is thought to reflect a placebo or anti-anxiety effect.…”

Topiramate for Posttraumatic Symptoms in an Obese Adolescent Girl

“…Given that D. was taking several psychotropic medications, it was not possible to conclude that her symptomatic improvement was related only to the addition of topiramate. We have previously commented on guanfacine's beneficial effect on PTSD symptoms (Anderson et al 2020) and facilitation of psychological therapy (Rice et al 2018). Of course, comprehensive psychosocial interventions in both attachment and trauma-focused insight-oriented therapy coupled with behavioral and cognitive-behavioral treatment were simultaneously administered, and likely contributed to her improvement.…”