GSH and Ferroptosis: Side-by-Side Partners in the Fight against Tumors
Yulang Jiang,
Christian Glandorff,
Mingyu Sun
Abstract:Glutathione (GSH), a prominent antioxidant in organisms, exhibits diverse biological functions and is crucial in safeguarding cells against oxidative harm and upholding a stable redox milieu. The metabolism of GSH is implicated in numerous diseases, particularly in the progression of malignant tumors. Consequently, therapeutic strategies targeting the regulation of GSH synthesis and metabolism to modulate GSH levels represent a promising avenue for future research. This study aimed to elucidate the intricate r… Show more
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